Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice

Lee James J.; Protheroe Cheryl A.; Luo Huijun; Ochkur Sergei I.; Scott Gregory D.; Zellner Katie R.; Raish Randall J.; Dahl Mark V.; Vega Miriam L.; Conley Olivia; Condjella Rachel M.; Kloeber Jake A.; Neely Joseph L.; Patel Yash S.; Maizer Patty; Mazzolini Andrew; Fryer Allison D.; Jacoby Noah W.; Jacoby David B.; Lee Nancy A.

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Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice

机译：小鼠接触毒物后嗜酸性粒细胞依赖性皮肤神经支配和瘙痒

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Background: Contact toxicant reactions are accompanied by localized skin inflammation and concomitant increases in site-specific itch responses. The role(s) of eosinophils in these reactions is poorly understood. However, previous studies have suggested that localized eosinophil-nerve interactions at sites of inflammation significantly alter tissue innervation.

机译：背景：接触性毒性反应伴有局部皮肤炎症，并伴随特定部位瘙痒反应的增加。嗜酸性粒细胞在这些反应中的作用知之甚少。但是，先前的研究表明，炎症部位的嗜酸性粒细胞-神经相互作用会显着改变组织的神经支配。

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《The Journal of Allergy and Clinical Immunology》 |2015年第2期|共11页
作者
Lee James J.; Protheroe Cheryl A.; Luo Huijun; Ochkur Sergei I.; Scott Gregory D.; Zellner Katie R.; Raish Randall J.; Dahl Mark V.; Vega Miriam L.; Conley Olivia; Condjella Rachel M.; Kloeber Jake A.; Neely Joseph L.; Patel Yash S.; Maizer Patty; Mazzolini Andrew; Fryer Allison D.; Jacoby Noah W.; Jacoby David B.; Lee Nancy A.;
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正文语种 eng
中图分类医学免疫学;
关键词
Contact hypersensitivity; eosinophil-deficient; sensory nerve; degranulation;

机译：接触性超敏;嗜酸性粒细胞缺乏;感觉神经;脱粒;

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1. Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice [J] . Lee James J., Protheroe Cheryl A., Luo Huijun, The Journal of Allergy and Clinical Immunology . 2015,第2期

机译：小鼠接触毒物后嗜酸性粒细胞依赖性皮肤神经支配和瘙痒
2. Prediction of itching diagnostic marker through RNA sequencing of contact hypersensitivity and skin scratching stimulation mice models [J] . Kim Young-Won, Zhou Tong, Ko Eun-A, The Korean Journal of Physiology & Pharmacology . 2019,第2期

机译：通过接触过敏和皮肤抓挠刺激小鼠模型的RNA测序预测瘙痒诊断标记
3. Skin exposure to weak and moderate contact allergens induces IFNgamma production by lymph node cells of CD4+ T-cell-depleted mice. [J] . Vocanson M, Hennino A, Rozieres A, The Journal of investigative dermatology. . 2009,第5期

机译：皮肤暴露于弱和中度接触变应原可诱导CD4 + T细胞耗竭小鼠的淋巴结细胞产生IFNγ。
4. Associations between Prenatal Toxicant Exposures and DNA Methylation at Birth and in Adolescence [C] . Jaclyn M. Goodrich, Dana C. Dolinoy, Wei Perng, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：产前和青春期产前毒物暴露与DNA甲基化之间的关联
5. Sympathetic sprouting and changes in nociceptive sensory innervation in the glabrous skin of the rat hind paw following partial peripheral nerve injury [D] . Yen, Laurene Dao-Pei 2007

机译：周围神经部分损伤后大鼠后足无毛皮肤的交感发芽和伤害性感觉神经的变化
6. Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice [O] . James J. Lee, Cheryl A. Protheroe, Huijun Luo, -1

机译：小鼠接触毒物后嗜酸性粒细胞依赖性皮肤神经支配和瘙痒
7. Prediction of itching diagnostic marker through RNA sequencing of contact hypersensitivity and skin scratching stimulation mice models [O] . Young-Won Kim, Tong Zhou, Eun-A Ko, 2019

机译：通过接触过敏和皮肤RNA测序对瘙痒诊断标志物的预测性抓刺激刺激小鼠模型
8. Thermoregulatory Responses to Environmental Toxicants: The Interaction of Thermal Stress and Toxicant Exposure [R] . Leon, L. R. 2008

机译：对环境毒物的体温调节反应：热应激和毒性暴露的相互作用

Eosinophil-dependent skin innervation and itching following contact toxicant exposure in mice

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