Utility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric Illnesses

Maekawa Motoko; Yamada Kazuo; Toyoshima Manabu; Ohnishi Tetsuo; Iwayama Yoshimi; Shimamoto Chie; Toyota Tomoko; Nozaki Yayoi; Balan Shabeesh; Matsuzaki Hideo; Iwata Yasuhide; Suzuki Katsuaki; Miyashita Mitsuhiro; Kikuchi Mitsuru; Kato Motoichiro; Okada Yohei; Akamatsu Wado; Mori Norio; Owada Yuji; Itokawa Masanari; Okano Hideyuki; Yoshikawa Takeo

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Utility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric Illnesses

机译：实用的头皮毛囊作为精神疾病的生物标志物基因的新型来源

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摘要

BACKGROUND: Identifying beneficial surrogate genetic markers in psychiatric disorders is crucial but challenging.

机译：背景：确定精神疾病中有益的替代遗传标记很关键，但具有挑战性。

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《Biological psychiatry》 |2015年第2期|共10页
作者
Maekawa Motoko; Yamada Kazuo; Toyoshima Manabu; Ohnishi Tetsuo; Iwayama Yoshimi; Shimamoto Chie; Toyota Tomoko; Nozaki Yayoi; Balan Shabeesh; Matsuzaki Hideo; Iwata Yasuhide; Suzuki Katsuaki; Miyashita Mitsuhiro; Kikuchi Mitsuru; Kato Motoichiro; Okada Yohei; Akamatsu Wado; Mori Norio; Owada Yuji; Itokawa Masanari; Okano Hideyuki; Yoshikawa Takeo;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Autism; CNTNAP2; FABP4; hsa-miR-4449; MicroRNA; Schizophrenia;

机译：自闭症;CNTNAP2;FABP4;hsa-miR-4449;MicroRNA;精神分裂症;

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专利

1. Utility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric Illnesses [J] . Maekawa Motoko, Yamada Kazuo, Toyoshima Manabu, Biological psychiatry . 2015,第2期

机译：实用的头皮毛囊作为精神疾病的生物标志物基因的新型来源
2. Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells [J] . Luis A. Garza, Chao-Chun Yang, Tailun Zhao, The journal of clinical investigation . 2011,第2期

机译：雄激素性脱发的男性头皮保留了毛囊干细胞，但缺乏富含CD200和CD34阳性的毛囊祖细胞
3. Morphometric analysis of the human scalp hair follicle: practical implications for the hair transplant surgeon and hair regeneration studies. [J] . Jimenez F, Izeta A, Poblet E Dermatologic surgery . 2011,第1期

机译：人类头皮毛囊的形态分析：对头发移植外科医师和头发再生研究的实际意义。
4. Hair Follicle Transplantation for the Treatment of the Linear Sclerocierma on the Scalp - a Case Report [C] . Fan Weixin, Zhou Naihui, Dai Yeqin International Congress of Dermatology . 2009

机译：头发卵泡移植治疗头皮上线性菌丝膜 - 案例报告
5. Genetic assay for estimating scalp hair pigmentation from forensic specimens. [D] . Jubelirer, Sara Lynn. 2010

机译：从法医标本估计头皮头发色素沉着的遗传测定。
6. Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression [O] . Kerstin Foitzik, Karoline Krause, Franziska Conrad, 2006

机译：人头皮毛囊既是催乳素的靶标又是催乳素的来源催乳素可作为细胞凋亡驱动的毛囊退化的自分泌和/或旁分泌促进剂。
7. Utility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric Illnesses [O] . Maekawa Motoko, Yamada Kazuo, Toyoshima Manabu, 2015

机译：实用的头皮毛囊作为精神疾病生物标志物基因的新来源
8. Hair Follicle Bulb as a Biodosimeter for Low-Level VX Vapor Exposure: Initial Studies Validating the Presence of Potential Protein Biomarkers of Exposure in the Sprague-Dawley Rat Whisker Follicle [R] . Chambers, A. E. , Benton, B. J. , Valdes, J. J. , 2006

机译：毛囊球泡作为低水平VX蒸气暴露的生物体测定仪：初步研究验证sprague-Dawley大鼠晶须卵泡中潜在的蛋白质生物标记物的存在

Utility of Scalp Hair Follicles as a Novel Source of Biomarker Genes for Psychiatric Illnesses

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