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首页> 外文期刊>The journal of clinical hypertension. >Performance of two metabolic syndrome definitions in the estimation of cardiovascular disease among hypertensive patients
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Performance of two metabolic syndrome definitions in the estimation of cardiovascular disease among hypertensive patients

机译：两种代谢综合征定义在高血压患者心血管疾病评估中的作用

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The authors evaluated the significance of metabolic syndrome (MetS) diagnosis, as defined by the National Cholesterol Education Program (NCEP) and by the International Diabetes Federation (IDF), in the evaluation of cardiovascular risk in hypertensive patients. Among 638 patients, the prevalence of MetS was 54.7% when the IDF criteria were used, compared with 45.5% when the NCEP criteria were used. MetS correlated significantly with the presence of cardiovascular disease (CVD). In patients without type 2 diabetes mellitus (T2DM), only MetS diagnosed using the IDF criteria was associated with the presence of CVD. In those with T2DM, MetS was not associated with CVD, regardless of the criteria used. The diagnosis of MetS, using either set of criteria, was associated with the development of T2DM. We conclude that, in hypertensive patients without diabetes, a diagnosis of MetS according to IDF criteria, but not the NCEP criteria, is useful in identifying individuals with a higher probability of incident CVD. In patients with diabetes, a population already considered at high risk for CVD, a diagnosis of MetS, regardless of the criteria used, has no further impact on prognosis.
机译：作者评估了由国家胆固醇教育计划（NCEP）和国际糖尿病联合会（IDF）定义的代谢综合征（MetS）诊断在评估高血压患者心血管风险中的重要性。在638例患者中，使用IDF标准时MetS的患病率为54.7％，而使用NCEP标准时为45.5％。 MetS与心血管疾病（CVD）的存在显着相关。在没有2型糖尿病（T2DM）的患者中，只有使用IDF标准诊断的MetS与CVD的存在相关。在患有T2DM的患者中，无论采用何种标准，MetS均与CVD无关。使用这两组标准对MetS的诊断与T2DM的发展有关。我们得出的结论是，在没有糖尿病的高血压患者中，根据IDF标准（而非NCEP标准）诊断MetS可用于识别发生CVD可能性较高的个体。在糖尿病患者中，已经被认为患有CVD的高风险人群，无论采用何种标准，MetS的诊断对预后均无进一步影响。

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