SYNTHESIS AND HALOGENATION OF PROPARGYL PYRAZOLO-[3,4-d]PYRIMIDINE THIOETHER

Onysko MY; Svalyavin OV; Turov AV; Lendel VG

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SYNTHESIS AND HALOGENATION OF PROPARGYL PYRAZOLO-[3,4-d]PYRIMIDINE THIOETHER

机译：丙基丙基吡唑并[3,4-d]嘧啶硫醚的合成与卤代反应

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The reaction of 4-imino-1-methyl-5-phenyl-6-propargylthio-1,5-dihydro-4H-pyrazolo[3,4-d ]pyrimidine with halogens leads to the formation of (Z)-8-halomethylene-4-imino-1-methyl-5-phenyl-4,5,7,8-tetrahydro-1H-pyr azolo[4,3-e][1,3]thiazolo[3,2-a]pyrimidinium trihalide.

机译：4-亚氨基-1-甲基-5-苯基-6-炔丙基硫基-1,5-二氢-4H-吡唑并[3,4-d]嘧啶与卤素的反应导致形成（Z）-8-卤代亚甲基-4-亚氨基-1-甲基-5-苯基-4,5,7,8-四氢-1H-pyr氮杂[4,3-e] [1,3]噻唑并[3,2-a]嘧啶三卤化物。

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《Chemistry of heterocyclic compounds》 |2008年第7期|共4页
作者
Onysko MY; Svalyavin OV; Turov AV; Lendel VG;
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正文语种 eng
中图分类杂环化合物;
关键词
4-imino-6-propargylthiopyrazolo3; 4-dpyrimidine; pyrazolo3; 4-dpyrimidine; trihalide; haloheterocyclization;

机译：4-亚氨基-6-炔丙基硫代吡唑并[3;4-d]嘧啶;吡唑并[3;4-d]嘧啶;三卤化物;卤代环化;

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1. SYNTHESIS AND HALOGENATION OF PROPARGYL PYRAZOLO-[3,4-d]PYRIMIDINE THIOETHER [J] . Onysko MY, Svalyavin OV, Turov AV, Chemistry of heterocyclic compounds . 2008,第7期

机译：丙基丙基吡唑并[3,4-d]嘧啶硫醚的合成与卤代反应
2. SYNTHESIS OF ALKYL THIOETHERS OF PYRAZOLO[3,4-d]PYRIMIDINE [J] . O.V.Svalyavin, M.Yu.Onysko, V. G. Lendel Chemistry of heterocyclic compounds . 2009,第7期

机译：吡唑并[3,4-d]嘧啶的烷基硫醚的合成
3. 1,5-Di-methyl-3′,5′-di-phenyl-1,5-di-hydro-3′H-spiro-[pyrazolo-[3,4-d]pyrimidine-4,2′-[1,3,4]-thia-diazole] [J] . Mohammed El Fal, Joel T. Mague, Jamal Taoufik, IUCrData . 2017,第7期

机译：1,5-二甲基-3'，5'-二苯基-1,5-二氢-3'H-螺螺（Pyrozolo-[3,4-D]嘧啶-4,2' - [ 1,3,4] - 脂肪唑类]
4. QSAR Study of Some Pyrazolo［3,4-d］pyrimidine Derivatives as the c-Src Inhibitors [C] . Bindesh Kumar Shukla, Umesh Yadava International Conference on Condensed Matter and Applied Physics . 2016

机译：一些吡唑基3,4-D嘧啶衍生物作为C-SRC抑制剂的QSAR研究
5. Control of Pyrimidine Biosynthesis in Pseudomonas aurantiaca by Pyrimidines [D] . Domakonda, Anvesh. 2018

机译：用嘧啶对吡啶基菌根的嘧啶生物合成的控制
6. Androgen Receptor Antagonists and Anti-Prostate Cancer Activities of Some Newly Synthesized Substituted Fused Pyrazolo- Triazolo- and Thiazolo-Pyrimidine Derivatives [O] . Saleh A. Bahashwan, Ahmed A. Fayed, Mohamed A. Ramadan, 2014

机译：雄激素受体拮抗剂和一些新合成的熔融吡唑并三唑并噻唑并嘧啶衍生物的抗前列腺癌活性
7. New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells [O] . Rossi, Alessandra, Schenone, Silvia, Angelucci, Adriano, 2010

机译：新型吡唑并[3,4-d]-嘧啶衍生物Src激酶抑制剂可导致人类髓母细胞瘤细胞停滞并减少肿瘤生长

SYNTHESIS AND HALOGENATION OF PROPARGYL PYRAZOLO-[3,4-d]PYRIMIDINE THIOETHER

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