New cytotoxic agents, BE-54238A and B, produced by a streptomycete

Tsukamoto M.; Murooka K.; Hirayama M.; Hirano K.; Yoshida S. Kojiri K.; Suda H.; Nakajima S.

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New cytotoxic agents, BE-54238A and B, produced by a streptomycete

机译：链霉菌产生的新细胞毒剂BE-54238A和B

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New cytotoxic substances, designated BE-54238A and B, were isolated from the culture broth of Streptomyces sp. A54238. The active principles were extracted from the mycelium by methanol and purified by Diaion HP-20 and Sephadex LH-20 column chromatographies. BE-54238A and B exhibited cytotoxic activity against murine and human tumor cell lines. [References: 10]

机译：从链霉菌属菌种的培养液中分离出新的细胞毒性物质，命名为BE-54238A和B。 A54238。用甲醇从菌丝体中提取活性成分，并通过Diaion HP-20和Sephadex LH-20柱色谱进行纯化。 BE-54238A和B对鼠和人肿瘤细胞系表现出细胞毒活性。 [参考：10]

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《The Journal of Antibiotics: An International Journal》 |2000年第1期|共7页
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Tsukamoto M.; Murooka K.; Hirayama M.; Hirano K.; Yoshida S. Kojiri K.; Suda H.; Nakajima S.;
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正文语种 eng
中图分类药学;药品;
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1. New cytotoxic agents, BE-54238A and B, produced by a streptomycete [J] . Tsukamoto M., Murooka K., Hirayama M., The Journal of Antibiotics: An International Journal . 2000,第1期

机译：链霉菌产生的新细胞毒剂BE-54238A和B
2. Combinatory cytotoxic effects produced by E1B-55kDa-deleted adenoviruses and chemotherapeutic agents are dependent on the agents in esophageal carcinoma [J] . G Ma, K Kawamura, Q Li, Cancer gene therapy . 2010,第11期

机译：由E1B-55kDa缺失的腺病毒和化疗药物产生的联合细胞毒作用取决于食道癌中的药物
3. Rhizosphere-competent isolates of streptomycete and non-streptomycete actinomycetes capable of producing cell-wall-degrading enzymes to control Pythium aphanidermatum damping-off disease of cucumber [J] . Khaled A El-Tarabily. Canadian Journal of Botany . 2006,第2期

机译：具有根际功能的链霉菌和非链霉菌放线菌的分离株，它们能够产生可降解细胞壁的酶来控制黄瓜枯萎病菌的衰减病
4. Cell-targeted cytotoxics: a new generation of cytotoxic agents for cancer treatment [C] . Christian Bailly An International Congress on Natural Anticancer Drugs . 2014

机译：细胞靶向细胞毒素：新一代细胞毒性剂用于癌症治疗
5. The Role if Amino Acid Metabolites on the Sensitivity to Cytotoxic Stress from Chemotherapeutic Agents [D] . Miles, Jana S. 2018

机译：如果氨基酸代谢物对来自化学治疗剂对细胞毒性胁迫的敏感性的作用
6. Combinatory cytotoxic effects produced by E1B-55kDa-deleted adenoviruses and chemotherapeutic agents are dependent on the agents in esophageal carcinoma [O] . G Ma, K Kawamura, Q Li, -1

机译：由E1B-55kDa缺失的腺病毒和化疗药物产生的联合细胞毒作用取决于食道癌中的药物
7. New Cytotoxic Agents, BE-54238A and B, Produced by a Streptomycete. [O] . MASAO TSUKAMOTO, SHIGERU NAKAJIMA, KUMIKO MUROOKA, 2000

机译：新的细胞毒性剂，BE-54238A和B，由链霉素产生。
8. Effect of Agents That Produce Membrane Disorder on Lysis of Erythrocytes by Complement (Complement Channels/Membrane Channels/Complement Cytotoxicity) [R] . Shin, M. L., Hansch, G., Mayer, M. M. 1981

机译：产生膜紊乱的药物通过补体（补体通道/膜通道/补体细胞毒性）对红细胞裂解的影响

New cytotoxic agents, BE-54238A and B, produced by a streptomycete

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