TPU-0031-A and B,New Antibiotics of the Novobiocin Group Produced by Streptomyces sp.TP-A0556

Tomomitsu Sasaki; Yasuhiro Igarashi; Noriko Saito; Tamotsu Furumai

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TPU-0031-A and B,New Antibiotics of the Novobiocin Group Produced by Streptomyces sp.TP-A0556

机译：TPU-0031-A和B，链霉菌种TP-A0556生产的新霉素新抗生素

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Two novel antibiotics,TPU-0031-A and B,were isolated from the culture broth of an actinomycete strain.The producing strain,TP-A00556,was identified as Streptomyces sp.Based on the Taxonomic study.The new antibiotics were obtained by solvent extraction and chromatographic purification.Spectroscopic analyses showed that TPU-0031-A and B were 7'-demethylnovobiocin and ;"-demethylnovbiocin,respectively.These compounds showed antibiotic activity against Gram-positive and -negative bacteria.

机译：从放线菌菌株的培养液中分离出两种新型抗生素TPU-0031-A和B.根据分类学研究，将生产菌株TP-A00556鉴定为链霉菌sp。光谱分析表明，TPU-0031-A和B分别为7'-去甲基新霉素和;“-去甲基新霉素。这些化合物对革兰氏阳性和阴性细菌均显示抗生素活性。

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《The Journal of Antibiotics: An International Journal》 |2001年第5期|共7页
作者
Tomomitsu Sasaki; Yasuhiro Igarashi; Noriko Saito; Tamotsu Furumai;
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正文语种 eng
中图分类药学;药品;
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1. TPU-0031-A and B,New Antibiotics of the Novobiocin Group Produced by Streptomyces sp.TP-A0556 [J] . Tomomitsu Sasaki, Yasuhiro Igarashi, Noriko Saito, The Journal of Antibiotics: An International Journal . 2001,第5期

机译：TPU-0031-A和B，链霉菌种TP-A0556生产的新霉素新抗生素
2. Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the Aminocoumarin Antibiotic Novobiocin [J] . Katrin Flinspach, Christian Rückert, J?rn Kalinowski, Genome Announcements . 2014,第1期

机译：链霉菌NCIMB 11891，氨基香豆素抗生素新霉素的生产者的基因组序列草案
3. Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the Aminocoumarin Antibiotic Novobiocin [J] . Katrin Flinspach, Christian Rückert, J?rn Kalinowski, Genome Announcements . 2014,第1期

机译：链霉菌NCIMB 11891，氨基香豆素抗生素新霉素的生产者的基因组序列草案
4. Isolation and screening of novel antibiotic producing Streptomyces from southwest Turkey soils [C] . A. Ugur, O. Ceylan International Conference on Antimicrobial Research . 2011

机译：来自西南土耳其土壤的新型抗生素生产链霉菌的分离与筛选
5. Genomic and proteomic exploration of regulatory pathways in antibiotic producing Streptomyces. [D] . Jayapal, Karthik Pennadam. 2008

机译：抗生素生产链霉菌中调控途径的基因组和蛋白质组学探索。
6. Draft Genome Sequence of Streptomyces niveus NCIMB 11891 Producer of the Aminocoumarin Antibiotic Novobiocin [O] . Katrin Flinspach, Christian Rückert, Jörn Kalinowski, 2014

机译：链霉菌NCIMB 11891氨基香豆素抗生素新霉素的生产者的基因组序列草案
7. Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the Aminocoumarin Antibiotic Novobiocin [O] . Katrin Flinspach, Christian Rückert, Jörn Kalinowski, 2014

机译：链霉菌肌草草草草案Niveus Niveus Ncimb 11891，Aminocoumarin抗生素脱蛋的生产者
8. Irradiation Studies of Local Streptomyces Strains for Higher Antibiotic Producing Capacity. Part of a Coordinated Programme on Radiation Microbiology. Final Report, for the Period 1 April 1974-30 June 1977 [R] . Kintanar, Q. L. 1978

机译：局部链霉菌菌株对高抗生素产生能力的辐照研究。辐射微生物学协调计划的一部分。最终报告，1974年4月1日至1977年6月1日

TPU-0031-A and B,New Antibiotics of the Novobiocin Group Produced by Streptomyces sp.TP-A0556

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