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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Action Mechanism of a Selective Anti-cyanobacterial Compound, Argimicin A
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Action Mechanism of a Selective Anti-cyanobacterial Compound, Argimicin A

机译：选择性抗蓝细菌化合物精氨酸A的作用机理

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摘要

Argimicin A is a potent anti-cyanobacterial compound produced by one of algae-lysing bacteria, Sphingomonas sp. M-17. Since the compound seemed o exhibit selective activities against cyanobacteria and such selectivity were considered to be quite rare, the mode of action of argimicin A was investigated. Argimicin A showed a unique delayed action, i.e., the cyanobacterial cell division continued until at least 36 hours treatment even though the decrement of oxygen evolution has been observed at 24 hours treatemnt. The compound is concluded to be a photosynthetic inhibitor which interrupts electron transport chain prior to photosystem II. From the reliminary fluorescent spectrum of argimicin A treated cyanobacterial cells, the site of action ws speculated to be photo energy transfer from a cyanobacterial specific complex of accessory protein pigments, phycobilisome, to photosystem II.
机译：Argimicin A是一种有效的抗蓝细菌化合物，由一种藻类裂解细菌Sphingomonas sp。产生。 M-17。由于该化合物似乎对蓝细菌表现出选择性活性，并且这种选择性被认为是非常罕见的，因此研究了精氨酸A的作用方式。尽管在24小时治疗时观察到氧气释放的减少，阿霉素A显示出独特的延迟作用，即，蓝细菌细胞分裂持续到至少36小时治疗。该化合物被认为是一种光合抑制剂，可在光系统II之前中断电子传输链。从经精氨酸A处理的蓝细菌细胞的初步荧光光谱中，推测其作用部位是光能从辅助蛋白色素的蓝细菌特异性复合物藻胆体转移至光系统II。

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