Byssochlamysol, a New Antitumor Steroid against IGF-1-dependent Cells from Byssochlamys nivea II. Physico-chemical Properties and Structure Elucidation

Toshiya Mori; Kazuo Shin-Ya; Kosuke Takarori; Maki Aihara; Yoichi Hayakawa

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Byssochlamysol, a New Antitumor Steroid against IGF-1-dependent Cells from Byssochlamys nivea II. Physico-chemical Properties and Structure Elucidation

机译：Byssochlamysol，一种新的抗类固醇，可对抗来自Byssochlamys nivea II的IGF-1依赖性细胞。理化性质和结构解析

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The structure of byssochlamysol, a new antitumor metabolite against IGF-1-dependent cancer cells from Byssochlamys nivea M#5187, was determined to be a highly oxidized ergostane steroid was shown in Fig. 1 by NMR studies. In the preceding paper, we have descibed the fermentation, isolation and biological activity of byssochlamysol, a new antitumor metabolite against IGF-1-dependent cancer cells as well as the taxonomy of the producing organism, Byssochlamys nieva M#5187.

机译：核磁共振研究表明，比索莫司醇是一种新的抗代谢产物，它来自尼古拉贝索莫司M＃5187，它是一种针对IGF-1依赖性癌细胞的新型抗肿瘤代谢产物，其结构如图1所示。在前面的文章中，我们描述了邻苯二甲酚的发酵，分离和生物学活性，该物质是一种新的针对IGF-1依赖性癌细胞的抗肿瘤代谢产物，并且与生产生物的分类法（Byssochlamys nieva M＃5187）有关。

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《The Journal of Antibiotics: An International Journal》 |2003年第1期|共3页
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Toshiya Mori; Kazuo Shin-Ya; Kosuke Takarori; Maki Aihara; Yoichi Hayakawa;
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正文语种 eng
中图分类药学;药品;
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1. Byssochlamysol, a New Antitumor Steroid against IGF-1-dependent Cells from Byssochlamys nivea II. Physico-chemical Properties and Structure Elucidation [J] . Toshiya Mori, Kazuo Shin-Ya, Kosuke Takarori, The Journal of Antibiotics: An International Journal . 2003,第1期

机译：Byssochlamysol，一种新的抗类固醇，可对抗来自Byssochlamys nivea II的IGF-1依赖性细胞。理化性质和结构解析
2. Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. II. Physico-chemical Properties and Structure Elucidation [J] . Ryo Murakami, Taijiro Tomikawa, Kazuo Shin-ya The Journal of Antibiotics: An International Journal . 2001,第9期

机译：Ammocidin，一种新的细胞凋亡诱导剂，来自Saccharothrix sp。的Ras依赖性细胞。二。理化性质和结构解析
3. Adxanthromycins A and B, new inhibitors of ICAM-1/LFA-1 mediated cell adhesion molecule from Streptomyces sp NA-148 II. Physico-chemical properties and structure elucidation [J] . Takahashi S., Koiwa T., Noshita T., The Journal of Antibiotics: An International Journal . 2000,第2期

机译：链霉素sp NA-148 II的ICAM-1 / LFA-1介导的细胞粘附分子的新抑制剂阿霉素A和B。理化性质和结构解析
4. Mass Spectrometry Analysis of Antitumor Steroidal Lactone Withaferin A Covalent Binding to Cysteine-303 of β-Tubulin in Human Breast Cancer Cells [C] . Guy T. Uechi, Marie Lue Antony, Eun-Ryeong Hahm, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：抗肿瘤甾体内酯的质谱分析与人乳腺癌细胞中β-微蛋白的半胱氨酸-303共价结合
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机译：一，抗老剂麻油酮的晶体和分子结构；二。两种嘧啶酮的晶体和分子结构；三，邻苯二甲酸酐的晶体和分子结构； IV。头孢洛辛酯，强效抗癌剂的侧链合成研究。
6. Towards sustainable processing of columbite group minerals: elucidating the relation between dielectric properties and physico-chemical transformations in the mineral phase [O] . Sergio Sanchez-Segado, Tamara Monti, Juliano Katrib, -1

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7. Ammocidin, a New Apoptosis Inducer in Ras-dependent Cells from Saccharothrix sp. II. Physico-chemical Properties and Structure Elucidation. [O] . RYO MURAKAMI, TAIJIRO TOMIKAWA, KAZUO SHIN-YA, 2001

机译：Ammocidin，来自Saccharothrix SP的RAS依赖性细胞中的一种新的凋亡诱导剂。 II。物理化学性质和结构阐明。

Byssochlamysol, a New Antitumor Steroid against IGF-1-dependent Cells from Byssochlamys nivea II. Physico-chemical Properties and Structure Elucidation

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