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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Antimycins A_(10)approxA_(16),Seven New Antimycin Antibiotics Produced by Streptomyces spy.SPA-10191 and SPA-8893
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Antimycins A_(10)approxA_(16),Seven New Antimycin Antibiotics Produced by Streptomyces spy.SPA-10191 and SPA-8893

机译:抗霉素A_(10)约A_(16),链霉菌间谍产生的七种新型抗霉素抗生素.SPA-10191和SPA-8893

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摘要

Seven new antimycin antibiotics,named antimycins A_(10),A_(11),A_(12),A_(13),A_(14),A_(15) and A_(16),were isolated from the fermentation broth of strains of Streptomyces spp.SPA-10191 and SPA-8893,along with known antimycins A_1,A_2,A_3 and A_4.The structures of the new antimycins were determined by spectral analyses,including 2D NMR techniques.These compounds exhibited antifungal activity against Candida utilis.
机译:从菌株的发酵液中分离出七种新的抗霉素抗生素,分别命名为抗霉素A_(10),A_(11),A_(12),A_(13),A_(14),A_(15)和A_(16)。链霉菌属SPA-10191和SPA-8893,以及已知的抗霉素A_1,A_2,A_3和A_4。通过光谱分析,包括2D NMR技术,确定了新的抗霉素的结构。这些化合物显示了对丝假丝酵母的抗真菌活性。

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