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首页> 外文期刊>The Journal of Antibiotics: An International Journal >Unnarmicins A and C, New Antibacterial Depsipeptides Produced by Marine Bacterium Photobacterium sp. MBIC06485.
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Unnarmicins A and C, New Antibacterial Depsipeptides Produced by Marine Bacterium Photobacterium sp. MBIC06485.

机译:Unnarmicins A和C,海洋细菌光细菌属sp。生产的新型抗菌二肽。 MBIC06485。

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摘要

Two new antibiotic depsipeptides, unnarmicins C (1) and A (2), were isolated from the fermentation broth of a marine bacterium, Photobacterium sp. strain MBIC06485. The structure of 1 was established by spectroscopic studies and chiral analyses of its chemical degradation/conversion products, and that of 2 by comparing its NMR, MS, and CD data with those of 1. Both compounds selectively inhibited the growth of two strains belonging to the genus Pseudovibrio, one of the most prevalent genera in the marine environments within the class Alphaproteobacteria.
机译:从海洋细菌Photobacter sp。的发酵液中分离出两种新的抗生素双肽肽unnarmicins C(1)和A(2)。菌株MBIC06485。 1的结构是通过光谱研究和手性分析对其化学降解/转化产物建立的,2的结构是通过将其NMR,MS和CD数据与1的结构进行比较的。这两种化合物选择性地抑制了两个属于假弧菌属,在海洋环境中最常见的一种,属于Alphaproteobacteria细菌类。

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