• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of Antibiotics: An International Journal >JBIR-31, a new teleocidin analog, produced by salt-requiring Streptomyces sp. NBRC 105896 isolated from a marine sponge.
【24h】

JBIR-31, a new teleocidin analog, produced by salt-requiring Streptomyces sp. NBRC 105896 isolated from a marine sponge.

机译：JBIR-31，一种新的telocicindin类似物，由需要盐的链霉菌属sp生产。 NBRC 105896从船用海绵中分离出来。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The marine environment has recently been described as a source of novel chemical diversity for drug discovery,1 as many bioactive substances are isolated from marine organisms including phytoplankton, algae, sponges, tunicates and mollusks.2,3 Our group has also reported the isolation of azaspiracid-24 and JBIR-445 from marine sponges. Microorganisms from marine habitats,6,7 especially actinobacteria, also constitute a promising untapped resource of novel compounds and are receiving special attention. Compared with higher organisms, microorganisms can be easily maintained under laboratory conditions ensuring a constant and inexpensive supply of their secondary metabolites. Moreover, compounds originally thought to be produced by a marine organism were later found to be produced by host-associated microorganisms.8 A significant body of work has emerged in the past 10 years on the isolation of actinobacteria from marine habitats and their screening has yielded several novel bioactive compounds.
机译：最近，海洋环境被描述为药物发现的新化学多样性的来源1，因为从海洋生物中分离出许多生物活性物质，包括浮游植物，藻类，海绵，被膜和软体动物[2,3]。海洋海绵中的azaspiracid-24和JBIR-445。来自海洋生境的微生物[6,7]，尤其是放线菌，也构成了有希望的尚未开发的新型化合物资源，受到了特别关注。与高等生物相比，微生物可以轻松地保持在实验室条件下，从而确保持续且廉价地供应其次级代谢产物。此外，最初被认为是由海洋生物产生的化合物后来被发现是由宿主相关的微生物产生的。8在过去十年中，从海洋生境中分离放线菌的工作已经出现了重要的工作，并且对其进行了筛选几种新颖的生物活性化合物。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号