ICM0201, a new inhibitor of osteoclastogenesis from cunninghammela sp. F-1490 II. Structure determination and synthesis

Tetsuya Someno; Hiroyuki Inoue; Hiroyuki Kumagai; Masaaki Ishizuka; Tomio Takeuchi

首页> 外文期刊>The Journal of Antibiotics: An International Journal >ICM0201, a new inhibitor of osteoclastogenesis from cunninghammela sp. F-1490 II. Structure determination and synthesis

【24h】

ICM0201, a new inhibitor of osteoclastogenesis from cunninghammela sp. F-1490 II. Structure determination and synthesis

机译：ICM0201，一种新的来自杉木的破骨细胞抑制剂。 F-1490 II。结构确定与综合

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

ICM0201 (1), a new inhibitor of murine osteoclastogenesis in culture was isolated from a fermentation broth of Cunninghamella sp. F-1490. The structure of ICM0201 was determined to be (3S, 10aR)-3,4a-dihydroxy-2,3,4,4a-tetrahydra-2H-pyrano[3,2-b]benzo[e]morpholine-9-carboxylic acid by spectroscopic analyses and chemical studies. The structure of 1 is unique in that the tricycle ring system is composed of aminal and hemiacetal bonds.

机译：从Cunninghamella sp。的发酵液中分离出ICM0201（1），一种新型的培养鼠源性破骨细胞抑制剂。 F-1490。确定ICM0201的结构为（3S，10aR）-3,4a-二羟基-2,3,4,4a-四氢-2H-吡喃并[3,2-b]苯并[e]吗啉-9-羧酸通过光谱分析和化学研究。 1的结构独特之处在于三环环系统由氨基键和半缩醛键组成。

著录项

来源
《The Journal of Antibiotics: An International Journal》 |2003年第3期|共5页
作者
Tetsuya Someno; Hiroyuki Inoue; Hiroyuki Kumagai; Masaaki Ishizuka; Tomio Takeuchi;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药学;药品;
关键词

相似文献

外文文献
中文文献
专利

1. ICM0201, a new inhibitor of osteoclastogenesis from cunninghammela sp. F-1490 II. Structure determination and synthesis [J] . Tetsuya Someno, Hiroyuki Inoue, Hiroyuki Kumagai, The Journal of Antibiotics: An International Journal . 2003,第3期

机译：ICM0201，一种新的来自杉木的破骨细胞抑制剂。 F-1490 II。结构确定与综合
2. SB-203207 and SB-203208, Two Novel Isoleucyl tRNA Synthetase Inhibitors from a Streptomyces sp. II. Structure Determination [J] . HOUGE-FRYDRYCH CATHERINE S., GILPIN MARTIN L., SKETT PETER W., The Journal of Antibiotics: An International Journal . 2000,第4期

机译：SB-203207和SB-203208，来自链霉菌属的两种新型异亮氨酰tRNA合成酶抑制剂。二。结构确定
3. SB-219383,a Novel Tyrosyl tRNA Synthestase Inhibitor from a Micromonospora sp. II. Structure Determination [J] . HOUGE-FRYDRYCH CATHERINE S.V., READSHAW SIMON A., BELL DAVID J. The Journal of Antibiotics: An International Journal . 2000,第4期

机译：SB-219383，来自Micromonospora sp。的新型酪氨酰tRNA合酶抑制剂。二。结构确定
4. Discovering Potent Inhibitors Against the β-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) of Helicobacter pylori: Structure-Based Design, Synthesis, Bioassay, and Crystal Structure Determination [C] . Lingyan He, Hualiang Jiang, Hong Liu, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：发现针对幽门螺杆菌的β-羟酰基-酰基载体蛋白脱水酶（FabZ）的有效抑制剂：基于结构的设计，合成，生物测定和晶体结构确定
5. Part I. Isolation of natural product inhibitors and synthesis of inhibitors of signal transduction. Part II. Structure-activity relationship for a series of glycosidase inhibitors. [D] . Fraser, Rebecca Dawn. 1993

机译：第一部分：天然产物抑制剂的分离和信号转导抑制剂的合成。第二部分一系列糖苷酶抑制剂的构效关系。
6. Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 138-triazaspiro45decan-4-one privileged structure that engenders PLD2 selectivity [O] . Robert Lavieri, Sarah A. Scott, Jana A. Lewis, -1

机译：同种型选择性磷脂酶D（PLD）抑制剂的设计与合成。第二部分。鉴定138-triazaspiro 45癸丹-4-一个特权结构用于参加PLD2选择性
7. TMC-86A, B and TMC-96, New Proteasome Inhibitors from Streptomyces sp. TC 1084 and Saccharothrix sp. TC 1094. II. Physico-chemical Properties and Structure Determination. [O] . YUTAKA KOGUCHI, JUN KOHNO, SFFLN-ICHI SUZUKI, 2000

机译：TMC-86A，B和TMC-96，来自Streptomyces SP的新蛋白酶体抑制剂。 TC 1084和Saccharothrix sp。 TC 1094.II。物理化学性质和结构测定。

ICM0201, a new inhibitor of osteoclastogenesis from cunninghammela sp. F-1490 II. Structure determination and synthesis

摘要

著录项

相似文献

相关主题

期刊订阅