Verticilide, a new ryanodine-binding inhibitor, produced by Verticillium sp. FKI-1033.

Shiomi K; Matsui R; Kakei A; Yamaguchi Y; Masuma R; Hatano H; Arai N; Isozaki M; Tanaka H; Kobayashi S; Turberg A; Omura S

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Verticilide, a new ryanodine-binding inhibitor, produced by Verticillium sp. FKI-1033.

机译：Verticilide是一种新的与ryanodine结合的抑制剂，由Verticillium sp。生产。 FKI-1033。

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A new ryanodine-binding inhibitor, verticilide, was isolated from the cultured broth of a fungus, Verticillium sp. FKI-1033. It is a 24-membered ring cyclic depsipeptide, its structure being elucidated as cyclo[(2R)-2-hydroxyheptanoyl-N-methyl- L-alanyl](4). Verticilide inhibited ryanodine binding to ryanodine receptors in the cockroach at an IC(50) value of 4.2 microM, whereas inhibition against mouse ryanodine receptors was weak (IC(50)=53.9 microM).

机译：从真菌黄萎病菌（Verticillium sp。）的培养液中分离出一种新的与ryanodine结合的抑制剂维替奇利德。 FKI-1033。它是一个24元环的环缩肽，其结构被阐明为环[（2R）-2-羟基庚酰基-N-甲基-L-丙氨酰基]（4）。黄腐素以4.2 microM的IC（50）值抑制蟑螂中的ryanodine与ryanodine受体的结合，而对小鼠ryanodine受体的抑制作用较弱（IC（50）= 53.9 microM）。

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《The Journal of Antibiotics: An International Journal》 |2010年第2期|共6页
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Shiomi K; Matsui R; Kakei A; Yamaguchi Y; Masuma R; Hatano H; Arai N; Isozaki M; Tanaka H; Kobayashi S; Turberg A; Omura S;
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中图分类药学;
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1. Verticilide, a new ryanodine-binding inhibitor, produced by Verticillium sp. FKI-1033. [J] . Shiomi K, Matsui R, Kakei A, The Journal of Antibiotics: An International Journal . 2010,第2期

机译：Verticilide是一种新的与ryanodine结合的抑制剂，由Verticillium sp。生产。 FKI-1033。
2. Verticipyrone, a New NADH-fumarate Reductase Inhibitor, Produced by Verticillium sp. FKI-1083 [J] . Hideaki Ui, Kazuro Shiomi, Hiroko Hatano, The Journal of Antibiotics: An International Journal . 2006,第12期

机译：Verticipyrone，一种新的NADH富马酸酯还原酶抑制剂，由Verticillium sp。生产。 FKI-1083
3. Verticillin A is likely not produced by Verticillium sp. [J] . Schenke D, Bottcher C, Lee J, The Journal of Antibiotics: An International Journal . 2011,第7期

机译：黄萎病菌可能不会产生黄萎病菌A。
4. ISOLATION OF PHYTOALEXINS FROM INDIGENOUS MALVACEAE SPECIES RESISTANT TO VERTICILLIUM DAHLIAE AND FUSARIUM OXYSPORUM F. SP. VASINFECTUM [C] . Olga Nikolaevna Veshkurova, Zamira Golubenko, Irina Arzanova, Beltwide Cotton Conference . 2006

机译：从土着麦芽糖素物种中植入植物的植物氧脂和镰刀菌镰刀菌的植物脂肪酸素。 vasinfectum.
5. Purification and characterization of elicitors from the wilt producing fungus, Verticillium dahliae, responsible for the induction of defense responses in plant cells [D] . Davis, David Alan 1992

机译：产生枯萎真菌黄萎病菌（Verticillium dahliae）诱导子的纯化和表征，负责诱导植物细胞中的防御反应
6. Draft Genome Sequence of the Volatile Organic Compound-Producing Antarctic Bacterium Arthrobacter sp. Strain TB23 Able To Inhibit Cystic Fibrosis Pathogens Belonging to the Burkholderia cepacia Complex [O] . Marco Fondi, Valerio Orlandini, Isabel Maida, 2012

机译：产生挥发性有机化合物的南极细菌节杆菌的基因组序列草图。能够抑制属于伯克霍尔德菌洋葱复合体的囊性纤维化病原菌的TB23菌株
7. Verticilide, a new ryanodine-binding inhibitor, produced by Verticillium sp. FKI-1033 [O] . Kazuro Shiomi, Ryosuke Matsui, Atsuo Kakei, 2010

机译：Verticilide，一种新的卤代胺结合抑制剂，由Verticillium sp产生。 FKI-1033.

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Verticilide, a new ryanodine-binding inhibitor, produced by Verticillium sp. FKI-1033.

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