JBIR-69, a new metabolite from Streptomyces sp. OG05.

Fujiwara T; Nagai A; Takagi M; Shin ya K

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JBIR-69, a new metabolite from Streptomyces sp. OG05.

机译：JBIR-69，来自链霉菌属的新代谢物。 OG05。

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Actinobacteria have been extensively studied thus far, and they are known to produce pharmaceutically important compounds.1,2 Soil serves as the primary source of actinobacteria and, therefore, we attempted to obtain novel metabolites from actinobacteria isolated from soil samples. During our screening program for novel metabolites, a new metabolite possessing a thioester named JBIR-69 (1, Figure 1a), together with a known compound, 3-isopropylmalate methyl ester, was isolated from the culture broth of Streptomyces sp. OG05. This paper describes the fermentation, isolation, structural elucidation, and, in brief, the biological activity of 1.

机译：迄今为止，放线菌已被广泛研究，并且已知它们会产生药学上重要的化合物。1,2土壤是放线菌的主要来源，因此，我们尝试从分离自土壤样品的放线菌中获得新的代谢产物。在我们对新型代谢物的筛选程序中，从链霉菌属菌种的培养液中分离出了一种新的代谢物，该代谢物具有名为JBIR-69的硫酯（图1a，图1a）以及已知的化合物3-异丙基苹果酸甲酯。 OG05。本文介绍了1.的发酵，分离，结构解析以及生物学活性。

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《The Journal of Antibiotics: An International Journal》 |2010年第2期|共2页
作者
Fujiwara T; Nagai A; Takagi M; Shin ya K;
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正文语种 eng
中图分类药学;
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1. JBIR-69, a new metabolite from Streptomyces sp. OG05. [J] . Fujiwara T, Nagai A, Takagi M, The Journal of Antibiotics: An International Journal . 2010,第2期

机译：JBIR-69，来自链霉菌属的新代谢物。 OG05。
2. Secondary Metabolites by Chemical Screening, 39 Acyl α-L-Rhamnopyranosides, a Novel Family of Secondary Metabolites from Streptomyces sp.: Isolation and Biosynthesis [J] . Stephanie Grond, Hans-Jorg Langer, Petra Henne, European journal of organic chemistry . 2000,第6期

机译：通过化学筛选产生的次级代谢产物，39个酰基α-L-鼠李糖吡喃糖苷，来自链霉菌属的新型次级代谢产物家族：分离和生物合成
3. Classification of novel soil streptomycetes as Streptomyces aureus sp. nov., Streptomyces laceyi sp. nov. and Streptomyces sanglieri sp. nov. [J] . Manfio GP, Atalan E, Zakrzewska Czerwinska J, Antonie van Leeuwenhoek: Journal of Microbiology and serology . 2003,第3期

机译：新型土壤链霉菌分类为金黄色链霉菌。十一月，Streptomyces laceyi sp.。十一月和链霉菌sanglieri sp。十一月
4. Knockout of N-hydroxybenzoate Hydroxylase Functional Gene Orf54 in Streptomyces sp. 13580 Gene Cluster and Fermentation Detection of Its Mutant Strain [C] . Zhen Meng, Yunhua Hou International Symposium on the Frontiers of Biotechnology and Bioengineering . 2019

机译：N-羟基苯甲酸盐羟化酶官能团基因组肌肉蛋白酶官能团ORF54。 13580基因簇和其突变菌株的发酵检测
5. Studies on nitrogen-containing secondary metabolites from terrestrial and marine origin: Part I. Enzymatic epoxidation of 2,5-dihydroxyacetanilide in Streptomyces sp. Part II. Synthesis of marine sponge alkaloids: Slagenins, axinohydantoins, and studies towards the pyrrolopiperazine system in the agelastatin core. [D] . Barrios Sosa, Ana Carolina. 2002

机译：陆生和海洋来源的含氮次生代谢产物的研究：第一部分。链霉菌属中2,5-二羟基乙酰苯胺的酶促环氧化。第二部分海洋海绵生物碱的合成：Slagenins，Axinohydantoins，以及在astlastatin核心中对吡咯烷哌嗪系统的研究。
6. Isolation and characterization of marine sponge–associated Streptomyces sp. NMF6 strain producing secondary metabolite(s) possessing antimicrobial antioxidant anticancer and antiviral activities [O] . Nayer Mohamed Fahmy, Asmaa Mohamed Abdel-Tawab 2021

机译：海绵伴相关链霉菌SP的分离与表征。产生具有抗菌抗氧化剂抗癌和抗病毒活性的次级代谢物的NMF6菌株
7. Anthracycline metabolites from baumycin-producing Streptomyces sp. D788. III. New anthracycline metabolites produced by blocked mutants 4L-660 and YDK-18. [O] . AKIHIRO YOSHIMOTO, OSAMU JOHDO, HIROSHI NISHIDA, 1993

机译：产生来自Baumycin的蒽环素代谢物Sp。 D788。 III。通过封闭突变体4L-660和YDK-18产生的新的蒽环素代谢物。

JBIR-69, a new metabolite from Streptomyces sp. OG05.

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