Erabulenols, inhibitors of cholesteryl ester transfer protein produced by Penicillium sp. FO-5637 - II. Structure elucidation of erabulenols A and B

Tabata N.; Omura S.; Tomoda H.

首页> 外文期刊>The Journal of Antibiotics: An International Journal >Erabulenols, inhibitors of cholesteryl ester transfer protein produced by Penicillium sp. FO-5637 - II. Structure elucidation of erabulenols A and B

【24h】

Erabulenols, inhibitors of cholesteryl ester transfer protein produced by Penicillium sp. FO-5637 - II. Structure elucidation of erabulenols A and B

机译：Erabulenols，由Penicillium sp。生产的胆固醇酯转移蛋白抑制剂。 FO-5637-II。皮质醇A和B的结构解析

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Structures of erabulenols A and B, novel fungal inhibitors of cholesteryl ester transfer protein were elucidated by spectroscopic studies including various NMR measurements. Erabulenols consist of a phenalenone skeleton and a 1,2,2-trimethyltetrahydrofuran moiety in common. Erabulenol B possesses an additional 2,6-dihydroxy-5-methyl-3-methylketonyl benzyl moiety. The absolute stereochemistry at the C-2' position of erabulenol A was deduced as S by comparison of the optical rotation with that of other related compounds. [References: 6]

机译：通过包括各种NMR测量在内的光谱研究阐明了胆甾醇A和B（胆甾醇酯转移蛋白的新型真菌抑制剂）的结构。肾上腺素共有一个菲苯酮骨架和一个1,2,2-三甲基四氢呋喃部分。戊烯醇B具有另外的2，6-二羟基-5-甲基-3-甲基酮基苄基部分。通过将旋光度与其他相关化合物的旋光度进行比较，得出了戊烯醇A的C-2'位置的绝对立体化学为S。 [参考：6]

著录项

来源
《The Journal of Antibiotics: An International Journal》 |1998年第7期|共5页
作者
Tabata N.; Omura S.; Tomoda H.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药学;药品;
关键词

相似文献

外文文献
中文文献
专利

1. Erabulenols, inhibitors of cholesteryl ester transfer protein produced by Penicillium sp. FO-5637 - II. Structure elucidation of erabulenols A and B [J] . Tabata N., Omura S., Tomoda H. The Journal of Antibiotics: An International Journal . 1998,第7期

机译：Erabulenols，由Penicillium sp。生产的胆固醇酯转移蛋白抑制剂。 FO-5637-II。皮质醇A和B的结构解析
2. New isochaetochromin, an inhibitor of triacylglycerol synthesis in mammalian cells, produced by Penicillium sp. FKI-4942: II. structure elucidation [J] . UgakiN., YamazakiH., UchidaR., The Journal of Antibiotics: An International Journal . 2012,第1期

机译：青霉素sp。生产的一种新的异色原色素，是哺乳动物细胞中三酰甘油合成的抑制剂。 FKI-4942：II。结构阐明
3. DISCOVERY, ISOLATION, STRUCTURE ELUCIDATION, AND BIOSYNTHESIS OF U-106305, A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR FROM UC 11136 [J] . Kuo MS., Cialdella JI., Marschke CK., Journal of the American Chemical Society . 1995,第43期

机译：UC 11136胆固醇酯转移蛋白抑制剂U-106305的发现，分离，结构鉴定和生物合成
4. Regulation of low density lipoprotein receptor-related protein gene expression, and, Cholesteryl ester transfer protein-mediated HDL selective uptake in the liver. [D] . Gauthier, Andre. 2006

机译：调节低密度脂蛋白受体相关蛋白基因的表达，以及胆固醇酯转移蛋白介导的HDL在肝脏中的选择性摄取。
5. Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins fibrates niacin and cholesteryl ester transfer protein inhibitors [O] . M. John Chapman, Wilfried Le Goff, Maryse Guerin, -1

机译：胆固醇酯转移蛋白：使用他汀类贝特类烟酸和胆固醇酯转移蛋白抑制剂进行脂质调节治疗的核心
6. Erabulenols, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Penicillium sp. FO-5637. II. Structure Elucidation of Erabulenols A and B. [O] . NORIKO TABATA, HIROSHI TOMODA, SATOSHI OMURA 1998

机译：Senicillium sp产生的橡皮烯醇，胆固醇酯转移蛋白的抑制剂。 FO-5637。 II。厄堡烯醇A和B的结构阐明。

Erabulenols, inhibitors of cholesteryl ester transfer protein produced by Penicillium sp. FO-5637 - II. Structure elucidation of erabulenols A and B

摘要

著录项

相似文献

相关主题

期刊订阅