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首页> 外文期刊>The Journal of craniofacial surgery >Pierre Robin Sequence and Treacher Collins Hypoplastic Mandible Comparison Using Three-Dimensional Morphometric Analysis
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Pierre Robin Sequence and Treacher Collins Hypoplastic Mandible Comparison Using Three-Dimensional Morphometric Analysis

机译：Pierre Robin序列和Treacher Collins利用三维形态计量分析进行下颌下颌骨发育不良的比较

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摘要

Pierre Robin sequence and Treacher Collins syndrome are both associated with mandibular hypoplasia. It has been hypothesized, however, that the mandible may be differentially affected. The purpose of this study was to therefore compare mandibular morphology in children with Pierre Robin sequence with children with Treacher Collins syndrome using three-dimensional analysis of computed tomographic scans. A retrospective analysis was performed identifying children with Pierre Robin sequence and Treacher Collins syndrome undergoing computed tomography. Three-dimensional reconstruction was performed, and ramus height, mandibular body length, and gonial angle were measured. These were then compared with those in control children with normal mandibles and with the clinical norms corrected for age and sex based on previously published measurements. Mandibular body length was found to be significantly shorter for children with Pierre Robin sequence, whereas ramus height was significantly shorter for children with Treacher Collins syndrome. This resulted in distinctly different ramus height-mandibular body length ratios. In addition, the gonial angle was more obtuse in both the Pierre Robin sequence and Treacher Collins syndrome groups compared with the controls. Three-dimensional mandibular morphometric analysis in patients with Pierre Robin sequence and Treacher Collins syndrome thus revealed distinctly different patterns of mandibular hypoplasiarelative to normal controls. These findings underscore distinct considerations that must be made in surgical planning for reconstruction.
机译：Pierre Robin序列和Treacher Collins综合征均与下颌发育不全相关。但是，据推测，下颌骨可能受到不同的影响。因此，本研究的目的是使用计算机断层扫描的三维分析比较皮埃尔·罗宾（Pierre Robin）序列患儿和特雷格·柯林斯综合征（Treacher Collins syndrome）儿童的下颌形态。进行了一项回顾性分析，确定了患有皮埃尔·罗宾序列和特雷格·科林斯综合征的儿童，他们正在接受计算机断层扫描。进行三维重建，并测量椎间盘高度，下颌体长和角向角。然后将这些与下颌骨正常的对照儿童以及根据先前公布的测量值校正的年龄和性别的临床规范进行比较。发现患有Pierre Robin序列的儿童的下颌体长明显短，而患有Treacher Collins综合征的儿童的下颌高明显短。这导致了明显不同的ramus高度-下颌体长比。此外，与对照组相比，皮埃尔·罗宾序列和特雷格·柯林斯综合症组的角性角更钝。皮埃尔·罗宾（Pierre Robin）序列和Treacher Collins综合征患者的三维下颌形态分析结果显示，与正常对照相比，下颌发育不全的模式明显不同。这些发现强调了在外科手术计划中必须进行的不同考虑。

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