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首页> 外文期刊>The Journal of Clinical Pharmacology: Official Journal of the American College of Clinical Pharmacology >Direct medical costs of liquid intravenous immunoglobulins in children, adolescents, and adults in Spain
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Direct medical costs of liquid intravenous immunoglobulins in children, adolescents, and adults in Spain

机译：西班牙儿童，青少年和成人的液体静脉注射免疫球蛋白的直接医疗费用

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摘要

The aim of this study was to determine health care resource utilization and direct medical costs in Spanish patients treated with intravenous immunoglobulins (IVIGs) in 2009. Cost-of-illness analyses were performed to estimate direct medical costs of patients treated with IVIGs. Prevalence data were obtained from the Spanish Primary Immunodeficiency registry. A semi-structured questionnaire was used to collect data on health care resource utilization and patient distribution. Drug, administration, and premedication costs were considered from the payer's perspective. Separate analyses were conducted for children and adolescents versus adults. The numbers of children and adolescents with replacement therapy were 724, with immunomodulation 243, and with allogeneic bone marrow transplantation 30. The numbers of adult patients were, respectively, 3450, 1134, and 172. Mean annual costs for children and adolescents were 6293 ? with Privigen, 6292 ? with Kiovig, 6939 ? with Flebogamma, and 6559 ? with Octagamocta. For adults, estimations were 17 106 ? with Privigen, 17 103 ? with Kiovig, 18 077 ? with Flebogamma, and 17 423 ? with Octagamocta. Direct medical costs for IVIGs were approximately 91.8 million ?. Drug costs represented 94% of total costs. The choice for a certain IVIG treatment depends on individual patient characteristics and cost considerations.
机译：这项研究的目的是确定2009年接受静脉免疫球蛋白（IVIG）治疗的西班牙患者的卫生保健资源利用率和直接医疗费用。进行了疾病费用分析，以估计接受IVIG治疗的患者的直接医疗费用。患病率数据是从西班牙主要免疫缺陷登记处获得的。使用半结构的调查表收集有关医疗资源利用和患者分布的数据。从付款人的角度考虑了药品，管理和处方药的费用。对儿童，青少年和成人分别进行了分析。接受替代疗法的儿童和青少年人数为724，接受免疫调节的儿童为243，接受异体骨髓移植的人数为30。成年患者的人数分别为3450、1134和172。儿童和青少年的年均费用为6293？与Privigen，6292？与Kiovig，6939吗？与Flebogamma和6559吗？与Octagamocta。对于成年人，估计为17106？与Privigen，17103吗？与Kiovig，18077吗？与Flebogamma，以及17423？与Octagamocta。 IVIG的直接医疗费用约为9180万欧元。药品费用占总费用的94％。某些IVIG治疗的选择取决于患者的个人特征和成本考虑。

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