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首页> 外文期刊>The Journal of Clinical Pharmacology: Official Journal of the American College of Clinical Pharmacology >Synergy Between Scientific Advancement and Technological Innovation, Illustrated by a Mechanism-Based Model Characterizing Sodium-Glucose Cotransporter-2 Inhibition
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Synergy Between Scientific Advancement and Technological Innovation, Illustrated by a Mechanism-Based Model Characterizing Sodium-Glucose Cotransporter-2 Inhibition

机译:科学进步与技术创新之间的协同作用,通过表征葡萄糖-葡萄糖共转运蛋白2抑制的基于机理的模型进行说明

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摘要

Advances in experimental medicine and technological innovation during the past century have brought tremendous progress in modern medicine and generated an ever-increasing amount of data from bench and bedside. The desire to extend scientific knowledge motivates effective data integration. Technological innovation makes this possible, which in turn accelerates the advancement in science. This mutually beneficial interaction is illustrated by the development of an expanded mechanism-based model for understanding a novel mechanism, sodium-glucose cotransporter-2 SGLT2 inhibition for potential treatment of type 2 diabetes mellitus.
机译:在过去的一个世纪中,实验医学和技术创新的进步为现代医学带来了巨大的进步,并且从工作台和床旁获得的数据量越来越多。扩展科学知识的愿望激发了有效的数据集成。技术创新使这成为可能,这反过来又加速了科学的进步。通过开发基于扩展机制的模型来说明这种互利的相互作用,该模型用于理解新型机制钠-葡萄糖共转运蛋白2 SGLT2抑制对2型糖尿病的潜在治疗作用。

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