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Differences in quality of life domains and psychopathologic and psychosocial factors in psychiatric patients.

机译:精神病患者的生活质量以及心理病理和社会心理因素的差异。

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BACKGROUND: Although treatment of severe mental disorders should strive to optimize quality of life (QOL) for the individual patient, little is known about variations in QOL domains and related psychopathologic and psychosocial factors in patients suffering from schizophrenia, schizoaffective disorder, and/or mood disorders. We hypothesized that QOL in severe mental disorder patients would have a more substantial relationship with psychosocial factors than with illness-associated factors. METHOD: A case-control, cross-sectional design was used to examine QOL of 210 inpatients who met DSM-IV criteria for a severe mental disorder and who were consecutively admitted to closed, open, and rehabilitation wards. Following psychiatric examination, 210 inpatients were assessed using standardized self-report measures of QOL, insight, medication side effects, psychological distress, self-esteem, self-efficacy, coping, expressed emotion, and social support. QOL ratings for patients and a matched control group (175 nonpatients) were compared. Regression and factor analyses were used to compare multidimensional variables between patients with schizophrenia and schizoaffective and mood disorders. RESULTS: In all QOL domains, patients were less satisfied than nonpatient controls. Patients with schizophrenia reported less satisfaction with social relationships and medication when compared with patients with schizoaffective and/or mood disorders. Regression analysis established differential clusters of predictors for each group of patients and for various domains of QOL. On the basis of the results of factor analysis, we propose a distress protection model to enhance life satisfaction for severe mental disorder patients. CONCLUSION: Psychosocial factors rather than psychopathologic symptoms affect subjective QOL of hospitalized patients with severe mental disorders. The findings enable better understanding of the combining effects of psychopathology and psychosocial factors on subjective life satisfaction and highlight targets for more effective intervention and rehabilitation.
机译:背景:尽管严重精神障碍的治疗应努力优化个体患者的生活质量(QOL),但对于患有精神分裂症,精神分裂症和/或情绪异常的患者的QOL域变化以及相关的心理病理和社会心理因素知之甚少疾病。我们假设重度精神障碍患者的生活质量与心理社会因素的关系要比与疾病相关因素的关系更为密切。方法:采用病例对照的横断面设计,对210名符合DSM-IV严重精神障碍标准并连续进入封闭,开放和康复病房的住院患者进行QOL检查。接受精神科检查后,使用QOL,见解,药物副作用,心理困扰,自尊,自我效能,应对,表达情绪和社会支持的标准化自我报告测量方法对210名住院患者进行评估。比较了患者和相匹配的对照组(175名非患者)的QOL评分。回归分析和因素分析用于比较精神分裂症和精神分裂症及情绪障碍患者的多维变量。结果:在所有QOL领域,患者的满意度均低于非患者对照组。与精神分裂症和/或情绪障碍患者相比,精神分裂症患者对社交关系和药物的满意度较低。回归分析为每组患者以及QOL的各个领域建立了不同的预测变量簇。基于因子分析的结果,我们提出了一种危重病人保护模型,以提高严重精神障碍患者的生活满意度。结论:社会心理因素而非精神病理学症状影响住院的重度精神障碍患者的主观生活质量。这些发现使人们能够更好地了解心理病理学和社会心理因素对主观生活满意度的综合作用,并突出了更有效干预和康复的目标。

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