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首页> 外文期刊>The journal of clinical psychiatry >Negative symptoms in depressed and schizophrenic patients: how do they differ?
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Negative symptoms in depressed and schizophrenic patients: how do they differ?

机译：抑郁症和精神分裂症患者的阴性症状：它们有何区别？

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BACKGROUND: The present study evaluated differences in negative symptoms between schizophrenic and depressive patients and investigated whether a consideration of the nature of negative symptoms (enduring vs. nonenduring) can help to improve their specificity for schizophrenia. METHOD: Patients enrolled in the study were consecutively hospitalized with an acute exacerbation of schizophrenia (N = 33) or major depressive disorder (N = 43) (DSM-IV). Negative and depressive symptoms were assessed with the Scale for the Assessment of Negative Symptoms (SANS) and the Montgomery-Asberg Depression Rating Scale, respectively. Duration of negative symptoms was assessed through a semistructured interview with the patients and their closest relatives. On the basis of the assessed duration of symptoms, negative symptoms were categorized as enduring or nonenduring. RESULTS: Analyses revealed high SANS ratings for both diagnostic groups. Negative symptoms in depressive patients (p =.01), but not in schizophrenic patients, were significantly associated with the presence or the emergence of depressive symptoms. The prevalence of enduring negative symptoms was significantly higher in schizophrenic patients than in depressive patients (p <.01). A consideration of enduring negative symptoms significantly increased the discriminative power of negative symptoms for schizophrenia (p =.02). CONCLUSION: The present findings suggest that negative symptoms in most depressive patients are just an epiphenomenon of depressive symptoms and can be distinguished from schizophrenic negative symptoms.
机译：背景：本研究评估了精神分裂症患者和抑郁症患者在阴性症状方面的差异，并调查了考虑负面症状的性质（持久性与非持久性）是否有助于提高其对精神分裂症的特异性。方法：参加研究的患者因精神分裂症急性加重（N = 33）或重度抑郁症（N = 43）（DSM-IV）连续住院。阴性和抑郁症状分别通过阴性症状评估量表（SANS）和蒙哥马利-阿斯伯格抑郁量表进行评估。阴性症状的持续时间通过对患者及其近亲的半结构式访谈进行评估。根据评估的症状持续时间，阴性症状分为持久性或非持久性。结果：分析显示两个诊断组的SANS评分较高。抑郁症患者的阴性症状（p = .01），而非精神分裂症患者则与抑郁症状的存在或出现显着相关。精神分裂症患者的持久阴性症状患病率显着高于抑郁症患者（p <.01）。考虑到持久的阴性症状可显着提高阴性症状对精神分裂症的鉴别力（p = .02）。结论：目前的发现表明，大多数抑郁症患者的阴性症状只是抑郁症状的一种现象，可以与精神分裂症阴性症状区分开。

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