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首页> 外文期刊>The journal of clinical psychiatry >Treatment of social phobia with antidepressants.
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Treatment of social phobia with antidepressants.

机译：用抗抑郁药治疗社交恐惧症。

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This article reviews evidence for the utility of antidepressant medications in the treatment of social phobia. Monoamine oxidase inhibitors (MAOIs) were the first antidepressants shown to be effective for social phobia, but dietary restrictions and a relatively high rate of adverse effects often relegate MAOIs to use after other treatments have been found ineffective. Reversible inhibitors of monoamine oxidase (RIMAs) hold promise as safer alternatives to MAOIs, but RIMAs may be less effective and are currently unavailable in the United States. Selective serotonin reuptake inhibitors (SSRIs), of which paroxetine has been the best studied in social phobia to date, have recently emerged as a first-line treatment for the generalized subtype of social phobia. The SSRIs are well tolerated and consistently have been shown to be efficacious in controlled trials.
机译：本文回顾了抗抑郁药在社交恐惧症治疗中的实用性的证据。单胺氧化酶抑制剂（MAOIs）是最早显示对社交恐惧症有效的抗抑郁药，但在发现其他治疗方法无效后，饮食限制和相对较高的不良反应率常常使MAOIs可以使用。单胺氧化酶（RIMA）的可逆抑制剂有望成为MAOI的更安全替代品，但RIMA的效力可能较低，目前在美国尚不可用。选择性5-羟色胺再摄取抑制剂（SSRIs），迄今为止，帕罗西汀在社交恐怖症中得到了最好的研究，最近已成为针对社交恐怖症亚型的一线治疗药物。 SSRI具有良好的耐受性，并且在对照试验中始终显示出其有效性。

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