首页> 外文期刊>The journal of clinical psychiatry >National trends in second-generation antipsychotic augmentation for nonpsychotic depression
【24h】

National trends in second-generation antipsychotic augmentation for nonpsychotic depression

机译:非精神病性抑郁症的第二代抗精神病药物治疗的国家趋势

获取原文
获取原文并翻译 | 示例
           

摘要

Objective: This study estimates national trends and patterns in use of second-generation antipsychotics (SGAs) for adjunctive treatment of nonpsychotic adult depression in office-based practice. Method: Twelve consecutive years (1999-2010) of the National Ambulatory Medical Care Survey were analyzed to estimate trends and patterns of adjunctive SGA treatment for adult (≥ 18 years) nonpsychotic depression in office-based visits. Adjunctive SGA use was examined among all office visits in which depression was diagnosed (N = 7,767), excluding visits with diagnoses for alternative SGA indications (schizophrenia, bipolar disorder, pervasive development disorder, psychotic depression, dementia) and those without an active antidepressant prescription. Results: From 1999 to 2010,8.6% of adult depression visits included an SGA. SGA use rates increased from 4.6% in 1999-2000 to 12.5% in 2009-2010, with an adjusted odds ratio (AOR) for time trend of 2.78 (95% CI, 1.84-4.20). The increase in SGA augmentation was broad-based, with no significant differences in time trends between demographic and clinical subgroups. For the most recent survey years (2005-2010), SGA use rates were higher in visits to psychiatrists than to other physicians (AOR=5.08; 95% CI, 2.96-8.73), visits covered by public than private insurance (AOR=3.20; 95% CI, 2.25-4.54), visits with diagnosed major depressive disorder than other depressive disorders (AOR= 1.49; 95% CI, 1.08-2.06), and visits with diabetes, hyperlipidemia, or cardiovascular disease (AOR=2.13; 95% CI, 1.12-4.03) and lower in visits by patients >65 years than 18-44 years (AOR=0.51; 95% CI, 0.32-0.82) and visits that included psychotherapy (AOR=0.68; 95% CI, 0.47-0.96). Conclusions: Between 1999 and 2010, SGAs were increasingly accepted in the outpatient treatment of adult nonpsychotic depression.
机译:目的:本研究估算了在办公室实践中使用第二代抗精神病药(SGA)辅助治疗非精神病性成人抑郁症的国家趋势和模式。方法:对《全国门诊医疗服务调查》连续十二年(1999年至2010年)进行分析,以评估在办公室就诊的成人(≥18岁)非精神病性抑郁症的辅助SGA治疗趋势和模式。在所有被诊断为抑郁症的办公室就诊中均检查了辅助性SGA的使用(N = 7,767),不包括具有其他SGA适应症(精神分裂症,双相情感障碍,普遍性发育障碍,精神病性抑郁症,痴呆)和没有有效抗抑郁药处方的诊断性就诊。结果:从1999年到2010年,8.6%的成人抑郁症就诊者包括SGA。 SGA的使用率从1999-2000年的4.6%增加到2009-2010年的12.5%,时间趋势调整后的优势比(AOR)为2.78(95%CI,1.84-4.20)。 SGA增强的增加是广泛的,人口统计学和临床​​亚组之间的时间趋势没有显着差异。在最近的调查年份(2005-2010年),精神科医师就诊的SGA使用率高于其他医师(AOR = 5.08; 95%CI,2.96-8.73),公共医疗的就诊率高于私人保险(AOR = 3.20) ; 95%CI,2.25-4.54),被诊断为重度抑郁症的探访比其他抑郁症(AOR = 1.49; 95%CI,1.08-2.06),以及患有糖尿病,高脂血症或心血管疾病的探访(AOR = 2.13; 95) %CI,1.12-4.03),> 65岁的患者访视要低于18-44岁(AOR = 0.51; 95%CI,0.32-0.82)和包括心理治疗的访视(AOR = 0.68; 95%CI,0.47- 0.96)。结论:在1999年至2010年期间,SGA在成人非精神病性抑郁症的门诊治疗中越来越多地被接受。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号