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Glutamatergic Dysregulation in Pediatric Psychiatric Disorders: A Systematic Review of the Magnetic Resonance Spectroscopy Literature

机译:小儿精神病患者的谷氨酸能调节异常:磁共振波谱学文献的系统综述

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摘要

Objective: As the major excitatory neurotransmitter in the brain, glutamate plays a critical role in normal brain function; thus, its dysregulation could lead to psychopathology in youth. A growing body of literature has investigated the role of glutamate in the pathophysiology of childhood psychiatric disorders through magnetic resonance spectroscopy (MRS). The aim of this study was to review the existing literature to gauge the specificity of such findings.
机译:目的:谷氨酸作为脑中主要的兴奋性神经递质,在正常脑功能中起着至关重要的作用。因此,它的失调可能导致青少年的精神病理学。越来越多的文献通过磁共振波谱(MRS)研究了谷氨酸在儿童精神疾病的病理生理中的作用。这项研究的目的是回顾现有文献以评估此类发现的特异性。

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