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首页> 外文期刊>The journal of clinical psychiatry >A trial of compliance therapy in outpatients with schizophrenia or schizoaffective disorder.
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A trial of compliance therapy in outpatients with schizophrenia or schizoaffective disorder.

机译：对精神分裂症或精神分裂症门诊患者进行依从性治疗的试验。

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OBJECTIVE: To evaluate the efficacy of compliance therapy when delivered to outpatients with schizophrenia or schizoaffective disorder. METHOD: Thirty patients with schizophrenia or schizoaffective disorder (DSM-IV criteria) were recruited from urban psychiatric outpatient clinics in an open trial of compliance therapy. Compliance therapy is a cognitive/psychoeducational approach consisting of 4 to 6 sessions lasting 30 to 60 minutes each. The primary outcome was electronically measured antipsychotic medication adherence. Adherence data were analyzed for effects during an initial treatment period (month -1 to month +1) and a subsequent 5-month follow-up period. Secondary outcome measures included clinician and patient ratings of adherence, symptoms, insight, and attitudes to medication treatment. Data were collected from August 2001 to January 2004. RESULTS: Compliance therapy was not associated with improvements in antipsychotic medication adherence. Patient ratings of adherence improved during the month -1 to month +1 period, but not in the subsequent 5-month follow-up. A diagnosis of schizoaffective disorder was associated with poorer adherence than was a diagnosis of schizophrenia during the month -1 to month +1 period. A higher degree of insight at baseline (end of month -1) was associated with greater adherence in the 5-month follow-up period. Symptoms, insight, and attitudes to medication treatment did not change significantly during the study. CONCLUSION: In this uncontrolled trial, outpatients with schizophrenia or schizoaffective disorder did not benefit from compliance therapy.
机译：目的：评估依从疗法在精神分裂症或精神分裂症门诊患者中的疗效。方法：从城市精神病门诊招募了30例精神分裂症或精神分裂症（DSM-IV标准）患者，进行了开放治疗。依从疗法是一种认知/心理教育方法，包括4至6个疗程，每次持续30至60分钟。主要结果是电子测量抗精神病药物依从性。分析在初始治疗期间（第-1个月至第+1个月）和随后的5个月随访期间的依从性数据。次要结果指标包括临床医生和患者对依从性，症状，洞察力和药物治疗态度的评级。结果收集自2001年8月至2004年1月。结果：依从性疗法与抗精神病药物依从性的改善无关。患者的依从性评分在-1个月至+1个月期间有所改善，但随后的5个月随访中没有改善。在-1个月至+1个月期间，与精神分裂症的诊断相比，精神分裂症的诊断与依从性差有关。基线（-1月末）的较高洞察力与5个月随访期间的依从性更高有关。在研究期间，症状，见识和对药物治疗的态度没有明显改变。结论：在这项非对照试验中，患有精神分裂症或精神分裂症的门诊患者没有从依从性治疗中受益。

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