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首页> 外文期刊>The journal of clinical psychiatry >Side effects of antipsychotics in the elderly.
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Side effects of antipsychotics in the elderly.

机译：老年人抗精神病药的副作用。

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摘要

Side effects of antipsychotic medications are particularly problematic in elderly patients, who experience many age-related changes that may exacerbate medication side effects. Side effects of particular concern in the elderly include anticholinergic reactions, parkinsonian events, tardive dyskinesia, orthostatic hypotension, cardiac conduction disturbances, reduced bone mineral density, sedation, and cognitive slowing. In addition, elderly patients with schizophrenia often have comorbid medical illnesses-such as cardiovascular disease and dementia of the Alzheimer's type-and are thus likely to be taking multiple medications. The effects of polypharmacy must be carefully considered. Patients, caregivers, and family often have different perspectives on side effects. This article addresses the side effects of the currently available antipsychotic medications in light of these concerns.
机译：抗精神病药物的副作用在老年患者中尤其成问题，老年患者经历许多与年龄有关的变化，这些变化可能加剧药物的副作用。老年人特别关注的副作用包括抗胆碱能反应，帕金森病，迟发性运动障碍，体位性低血压，心脏传导障碍，骨矿物质密度降低，镇静和认知减慢。另外，患有精神分裂症的老年患者经常患有合并症，例如心血管疾病和阿尔茨海默氏型痴呆症，因此很可能正在服用多种药物。必须仔细考虑多元药房的作用。患者，护理人员和家庭对副作用的看法往往不同。鉴于这些问题，本文介绍了目前可用的抗精神病药物的副作用。

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