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QTc and metabolic parameters.

机译:QTc和代谢参数。

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My colleagues and I have been interested in QTc interval prolongation, torsade de pointes, and antipsychotic drugs for some time. The article by Mackin and Young in the November 2005 issue of the Journal has sufficient limitations both in its own right and as a model for a larger study to stimulate the following comments:In the Introduction, Mackin and Young assert a need to examine "the relationship between QTc interval, anti-psychotic use, and metabolic dysfunction. Theauthors do not mention plasma or serum potassium concentrations and are seemingly unaware that low potassium states are far and away the most common cause of QTc interval prolongation.
机译:我和我的同事们对QTc间隔延长,足尖扭转和抗精神病药物感兴趣已有一段时间了。 Mackin and Young在《华尔街日报》 2005年11月号上发表的文章在其本身和作为较大研究的模型上都有足够的局限性,以激发以下评论:在引言中,Mackin and Young主张有必要研究“ QTc间隔,抗精神病药的使用和代谢功能障碍之间的关系作者没有提及血浆或血清钾浓度,而且似乎没有意识到低钾状态已成为QTc间隔延长的最常见原因。

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