Revisiting monoamine oxidase inhibitors.

Krishnan KR

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Revisiting monoamine oxidase inhibitors.

机译：回顾单胺氧化酶抑制剂。

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Monoamine oxidase inhibitors (MAOIs) were among the first class of agents introduced for the treatment of depression. However, they have fallen out of favor among clinicians over the years, due mostly to an unfavorable safety profile, the need for restrictive dietary prohibitions, and the fear of hypertensive crisis. The development of a novel, transdermal MAOI system now offers clinicians an additional option for managing patients with unipolar, bipolar, atypical, and treatment-resistant depression.

机译：单胺氧化酶抑制剂（MAOIs）是用于治疗抑郁症的第一类药物。但是，由于安全性不佳，饮食限制饮食的需求以及对高血压危机的恐惧，多年来，它们在临床医生中一直不受欢迎。现在，新型透皮MAOI系统的开发为临床医生提供了治疗单相，双相，非典型和难治性抑郁症患者的另一种选择。

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《The journal of clinical psychiatry》 |2007年第8期|共7页
作者
Krishnan KR;
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正文语种 eng
中图分类精神病学;
关键词
Monoamine Oxidase Inhibitors; Cancer patients and suicide and depression;

机译：单胺氧化酶抑制剂;癌症患者与自杀和抑郁症;

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1. Revisiting monoamine oxidase inhibitors. [J] . Krishnan KR The journal of clinical psychiatry . 2007,第Suppla8期

机译：回顾单胺氧化酶抑制剂。
2. Advances pertaining to the pharmacology and interactions of irreversible nonselective monoamine oxidase inhibitors. [J] . Gillman PK Journal of clinical psychopharmacology . 2011,第1期

机译：不可逆的非选择性单胺氧化酶抑制剂的药理作用和相互作用的研究进展。
3. Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors. [J] . Herraiz T, Guillen H Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research . 2011,第8期

机译：抗氧化剂，氧化还原剂和单胺氧化酶抑制剂抑制神经毒素MPTP的生物活化。
4. INVESTIGATION OF MONOAMINE OXIDASE INHIBITORY ACTIVITIES OF NEW CHALCONE DERIVATIVES: COMPARISON OF LC-MS/MS AND FLUOROMETRIC METHODS [C] . Umide Demir Ozkay, Nafiz Oncu Can, Serkan Levent, International Mass Spectrometry Conference . 2018

机译：新硫酮衍生物单胺氧化酶抑制活性的研究：LC-MS / MS和荧光法的比较
5. Expression and functional characterization of monoamine oxidase from the zebrafish (Danio rerio): Comparisons with human monoamine oxidases A and B. [D] . Kacar, Betul. 2009

机译：斑马鱼（Danio rerio）单胺氧化酶的表达和功能表征：与人单胺氧化酶A和B的比较。
6. Proceedings: Monoamine oxidase active site; the binding to and titration of monoamine oxidase with (14C)-selective inhibitors. [O] . M B Youdim 1976

机译：论文集：单胺氧化酶活性位点；（14C）-选择性抑制剂与单胺氧化酶的结合和滴定。
7. Synthesis and molecular modelling of novel substituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase-A inhibitors. [O] . CHIMENTI F, BOLASCO A, MANNA F, 2006

机译：新型取代的4,5-二氢-（1H）-吡唑衍生物作为强效和高选择性单胺氧化酶-A抑制剂的合成与分子模型。

Revisiting monoamine oxidase inhibitors.

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