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Treatment recommendations versus treatment realities: recognizing the rift and understanding the consequences.

机译:治疗建议与治疗现实:认识裂痕并了解后果。

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摘要

Depression is a treatable disorder, although it often requires long-term therapy. To aid physicians in the effective long-term management of depression, treatment guidelines have been established by a number of organizations with minimum treatment duration recommendations. Unfortunately, numerous studies document a significant disparity between these recommendations and clinical practice realities. In particular, studies have shown that fewer than half of treated patients receive the recommended duration of 6 months of continuation therapy. Other clinical practice studies have reported that early discontinuation from therapy is associated with a substantial increase in the risk of relapse or recurrence. Long-term treatment of depression in clinical practice settings may benefit from a closer approximation to the conditions found in clinical trial settings.
机译:抑郁症是可以治疗的疾病,尽管它经常需要长期的治疗。为了帮助医生有效地长期治疗抑郁症,许多组织制定了治疗指南,并建议了最短的治疗时间。不幸的是,大量研究表明,这些建议与临床实践之间存在巨大差异。特别是,研究表明,只有不到一半的接受治疗的患者接受了建议的持续治疗6个月的持续时间。其他临床实践研究报道,早期停止治疗与复发或复发风险的显着增加有关。在临床实践环境中对抑郁症的长期治疗可能会受益于更接近于临床试验环境中发现的疾病。

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