• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of clinical psychiatry >Is psychopharmacologic treatment associated with neuropsychological deficits in bipolar youth?
【24h】

Is psychopharmacologic treatment associated with neuropsychological deficits in bipolar youth?

机译：躁郁症患者的心理药物治疗是否与神经心理缺陷相关？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: To evaluate the impact of psychopharmacologic treatments on neuropsychological functioning in bipolar youth. METHOD: Participants were 173 children (aged 6-17 years) with DSM-IV bipolar disorder. Participants were comprehensively assessed using structured diagnostic interviews (Schedule for Affective Disorders and Schizophrenia for School-Age Children) and neuropsychological measures (eg, subtests of the Wechsler Intelligence Scale for Children-III and Wechsler Adult Intelligence Scale-III) during the years 2001-2006. Comparisons were made in neuropsychological functioning between medicated and unmedicated youth with bipolar disorder. RESULTS: Children who were treated with mood stabilizers performed significantly (P < .05) more poorly than untreated children on measures of processing speed and working memory. Treatment with other classes of medication, including second-generation antipsychotics, was not significantly associated with neuropsychological impairments. CONCLUSIONS: Treatment with mood stabilizers may be associated with specific neuropsychological impairments. Cognitive side effects may need to be considered in selecting particular psychopharmacologic treatments for children with bipolar disorder.
机译：目的：评估心理药物治疗对双相型青少年神经心理功能的影响。方法：参与者为173名6至17岁的DSM-IV双相情感障碍儿童。在2001-2001年间，通过结构性诊断访谈（情感障碍时间表和学龄儿童精神分裂症）和神经心理学措施（例如，儿童III韦氏智力量表和III韦氏成人智力量表的子测验）对参与者进行了全面评估。 2006年。进行了药物治疗和未药物治疗的躁郁症青年在神经心理功能方面的比较。结果：在处理速度和工作记忆方面，使用情绪稳定剂治疗的儿童比未治疗的儿童表现明显差（P <.05）。其他类别的药物（包括第二代抗精神病药）的治疗与神经心理学障碍没有显着相关性。结论：用情绪稳定剂治疗可能与特定的神经心理学障碍有关。选择双相情感障碍儿童的特殊心理药物治疗时，可能需要考虑认知副作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号