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Generalized anxiety disorder and psychiatric comorbidities such as depression, bipolar disorder, and substance abuse.

机译:广泛性焦虑症和精神病合并症,例如抑郁症,躁郁症和药物滥用。

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摘要

Generalized anxiety disorder (GAD) has a high rate of comorbidity with other psychiatric disorders, including major depressive disorder (MDD), bipolar disorder, other anxiety disorders, and substance use disorders. The similarities between GAD and MDD have led some to suggest that GAD should be reclassified as a mood disorder. The concurrence of GAD with another disorder heightens a patient's risk for impairment, disability, and suicidality. Clinical trials for GAD and disorders that are most likely to occur with GAD have generally not taken comorbidity into account, and there is a paucity of data guiding how comorbidity should inform treatment selection. Research into the biology and psychopathology underlying the high rate of comorbidity of GAD and into efficacious interventions for GAD with comorbidity is needed.
机译:广泛性焦虑症(GAD)与其他精神病合并症的发病率很高,包括严重抑郁症(MDD),躁郁症,其他焦虑症和药物滥用症。 GAD和MDD之间的相似性使一些人建议GAD应该重新分类为情绪障碍。 GAD与另一种疾病的并发会增加患者发生损伤,残疾和自杀的风险。 GAD和最有可能发生在GAD中的疾病的临床试验通常没有考虑合并症,并且缺乏指导合并症如何指导治疗选择的数据。需要对高GAD合并症发病率的生物学和心理病理学进行研究,以及对合并症的GAD进行有效干预的研究。

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