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首页> 外文期刊>The Journal of dermatology >Glomangiosarcoma of the hand: a case report and review of the literature.
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Glomangiosarcoma of the hand: a case report and review of the literature.

机译：手的血管肉瘤：病例报告和文献复习。

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摘要

Glomangiosarcomas, or malignant glomus tumors, are very rare, cutaneous, soft tissue tumors. Despite having histologic features of malignancy, these tumors usually do not metastasize. We describe a 74-year-old woman with a glomangiosarcoma on her hand and review the literature. The woman presented with a five month history of a painful mass on the right palm. An excisional biopsy of the mass was undertaken. Histologically, the tumor was composed of uniform, round cells and numerous vascular components. The tumor cells were pleomorphic and had large nucleoli. Frequent mitotic figures were identified. Immunohistochemical stains showed strong positivity for vimentin and weak, focal positivity for smooth muscle actin. Ultrastructurally, the tumor cells were characterized by pinocytic vesicles, well formed basal lamina, and scattered junctional complex of the plasma membrane.
机译：血管肉瘤或恶性球瘤是非常罕见的皮肤软组织肿瘤。尽管具有恶性的组织学特征，但这些肿瘤通常不转移。我们描述了一名74岁的女性，手上有血管肉瘤，并对其文献进行了回顾。该妇女在右手掌上出现了五个月的疼痛性肿块病史。对该肿块进行切除活检。在组织学上，肿瘤由均匀的圆形细胞和许多血管成分组成。肿瘤细胞是多形的，具有大核仁。确定了频繁的有丝分裂图。免疫组织化学染色显示波形蛋白强，而平滑肌肌动蛋白则弱。在超微结构上，肿瘤细胞的特征是小球囊泡，良好形成的基底层和质膜的分散连接复合物。

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