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首页> 外文期刊>The Journal of dermatology >Cutaneous pseudolymphoma caused by tumor necrosis factor-alpha Inhibitors was not induced by ustekinumab
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Cutaneous pseudolymphoma caused by tumor necrosis factor-alpha Inhibitors was not induced by ustekinumab

机译:ustekinumab不会诱导由肿瘤坏死因子-α抑制剂引起的皮肤假性淋巴瘤

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摘要

Two different types of biologic reagents are currently used for the treatment of psoriasis, namely tumor necrosis factor (TNF)-alpha inhibitors and an anti-interleukin (IL)-12/23 p40 antibody reagent, ustekinumab (UST). Although these two types of drugs have similar dramatic therapeutic effects on psoriatic lesions, their adverse events seem to differ. TNF-alpha inhibitors bring unexpected immune-related conditions such as a palmoplantar pustulosis-like eruption often called a "paradoxical reaction". We previously reported a case of pseudolymphoma induced by both adalimumab (ADM) and infliximab (IFX).
机译:目前,两种不同类型的生物试剂用于治疗牛皮癣,即肿瘤坏死因子(TNF)-α抑制剂和抗白介素(IL)-12/23 p40抗体试剂ustekinumab(UST)。尽管这两种类型的药物对银屑病皮损具有相似的戏剧性治疗效果,但它们的不良反应似乎有所不同。 TNF-α抑制剂会带来意想不到的与免疫有关的疾病,如掌plant脓疱样样疹,通常被称为“悖论性反应”。我们之前曾报道过由阿达木单抗(ADM)和英夫利昔单抗(IFX)诱导的假性淋巴瘤病例。

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