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首页> 外文期刊>The Journal of dermatology >Basal cell carcinoma with an epidermal collarette and ductal differentiation on the dorsal foot
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Basal cell carcinoma with an epidermal collarette and ductal differentiation on the dorsal foot

机译：基底细胞癌，表皮颈圈和背足管分化

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摘要

Basal cell carcinomas (BCC) usually develop on the face and neck. Fewer than 30 cases (0.42%) of BCC have been reported on the feet in the English-language published work.1 Only two cases have been reported on the dorsal feet, while the majority developed on the sole. An 89-year-old man presented with a 2-year history of a tumor on the left dorsal foot. The clinical appearance was a well demarcated, dome-shaped, dark-red to blue-gray nodule measuring 10 mm in diameter (Fig. 1). Dermbscopy demonstrated large blue-gray ovoid nests, multiple blue-gray globules and arborizing vessels. A homogeneous white ring surrounded these structures. Histological examination demonstrated variously shaped islands with cyst formation and lace-like pattern, which was composed of basaloid cells (Fig. 2a). Several ducts within tumor islands were lined by luminar cells as seen in normal eccrine/apocrine ducts and poromas (Fig. 2b). Elongated rete ridges at the periphery of the nodule demonstrated infolding toward the center and partial ductal structures, corresponding to an epidermal collarette (Fig. 2a). Although peripheral palisading was clearly observed, there were no obvious clefts.
机译：基底细胞癌（BCC）通常在面部和颈部发展。在英语发表的工作中，脚部报告BCC的病例少于30例（0.42％）。1背脚仅报告了2例，而足底则报告了大部分。一位89岁的男性患者出现了左背脚肿瘤2年的病史。临床表现为边界清晰，圆顶形，深红色至蓝灰色结节，直径为10 mm（图1）。皮肤镜检查显示出大的蓝灰色卵形巢，多个蓝灰色小球和乔木容器。均匀的白环包围了这些结构。组织学检查显示形状多样的岛，具有囊肿形成和类似花边的图案，由基底细胞组成（图2a）。如正常的内分泌/顶泌管和孔瘤中所见，肿瘤岛内的几个导管被腔内细胞排列（图2b）。结节周边的网状long突向中央和部分导管结构折叠，与表皮颈圈相对应（图2a）。尽管清楚地观察到周围麻痹，但没有明显的裂口。

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