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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >HCG-A new kid on the block in prematurity prevention.
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HCG-A new kid on the block in prematurity prevention.

机译：HCG-预防早产的新手。

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摘要

Human chorionic gonadotropin (HCG) is a molecule with multiple endocrine, paracrine, and immunoregulatory actions. Its importance for the enhancement of fertility, successful implantation, and survival of the conceptus in early gestation is recognized. However, studies conducted worldwide in recent years indicate that HCG may also play a significant role in maintaining pregnancy well after the first trimester. Emerging evidence suggests that different biomolecular and physiologic effects of HCG are concordantly directed toward inhibition of myometrial contractility to maintain pregnancy. These studies have prompted preliminary animal and human testing of HCG for the prevention of preterm birth. This article reviews the current knowledge as well as the future perspectives on HCG as a useful new tool in prematurity prevention.
机译：人绒毛膜促性腺激素（HCG）是具有多种内分泌，旁分泌和免疫调节作用的分子。人们认识到其对于提高生育力，成功植入以及早期妊娠中胎的存活的重要性。但是，近年来在全球范围内进行的研究表明，HCG在早孕后的良好维持妊​​娠方面也可能起着重要作用。新兴证据表明，HCG的不同生物分子和生理作用一致地指向抑制子宫肌层收缩以维持妊娠。这些研究促进了HCG的动物和人体的初步测试，以预防早产。本文回顾了有关HCG作为预防早产的有用新工具的当前知识以及未来观点。

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