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首页> 外文期刊>The journal of maternal-fetal & neonatal medicine >Cluster of late preterm and term neonates with necrotizing enterocolitis symptomatology: descriptive and case-control study
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Cluster of late preterm and term neonates with necrotizing enterocolitis symptomatology: descriptive and case-control study

机译：早产和足月新生儿坏死性小肠结肠炎症状的群集：描述性和病例对照研究

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Objective: To investigate a necrotizing enterocolitis (NEC) cluster of late preterm and term neonates (gestational age34 weeks).Methods: We conducted a descriptive and a case-control study. Medical records of neonates with modified Bell stageIB NEC and matched controls were reviewed, in addition to microbiological and environmental investigation. Study variables included maternal/delivery and neonatal factors, medications, procedures and feeding practices. Univariable/multivariable logistic regression analyses were performed for all and for stageII cases.Results: Out of 1841 late preterm and term neonates, 10 stage IB and 10 stageII [mean(SD) birthweight 2529.3 (493.04) g, gestational age 36.96 (1.48) weeks] presented with NEC symptomatology at mean 4.6 (range 2-8) days. Nearly all (19/20) resulted from high-risk pregnancies and received postpartum intermediate care. All were exclusively or partly formula fed. Most (14/20) were born by cesarean delivery. Eight underwent surgery, with no fatality. Intermediate care (p=0.006), transient tachypnea (p=0.049), not receiving breast milk (p=0.019) and in addition intrauterine growth restriction (IUGR) (p=0.017) for stageII cases were independently associated with NEC.Conclusions: Late preterm and term neonates in need of intermediate care, with IUGR and transient tachypnea were susceptible to NEC; feeding with breast milk was an important protective factor.
机译：目的：研究早产和足月新生儿（胎龄34周）的坏死性小肠结肠炎（NEC）。方法：我们进行了描述性和病例对照研究。除微生物和环境调查外，还对具有改良的Bell stageIB NEC和匹配对照的新生儿的病历进行了审查。研究变量包括产妇/分娩和新生儿因素，药物，程序和喂养方式。结果：在1841例早产和足月新生儿中，有10例IB期和10例II期[平均（SD）出生体重2529.3（493.04）g，胎龄36.96（1.48）”进行了单变量/多变量logistic回归分析。周]出现平均4.6天（范围2-8天）的NEC症状。几乎所有（19/20）患者均来自高危妊娠，并接受了产后中间护理。全部全部或部分用配方奶喂养。大多数（14/20）是通过剖腹产出生的。八人接受了手术，无死亡。 II期患者的中间护理（p = 0.006），短暂性呼吸急促（p = 0.049），未接受母乳（p = 0.019）以及宫内生长受限（IUGR）（p = 0.017）与NEC独立相关。需要中间护理，IUGR和短暂性呼吸急促的早产和足月新生儿容易患NEC;母乳喂养是重要的保护因素。

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