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首页> 外文期刊>The journal of ECT >Seizures induced by low-dose right unilateral and bifrontal electroconvulsive stimuli.
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Seizures induced by low-dose right unilateral and bifrontal electroconvulsive stimuli.

机译：小剂量右单侧和双额电惊厥刺激引起的癫痫发作。

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SUMMARY: The duration of electroconvulsive therapy (ECT) seizures of depressive patients has been found to be inversely related to titrated right unilateral (RUL) and bilateral (BL) seizure threshold (ST) levels. This inverse relationship is thought to reflect those neural processes determining seizure duration. The relation between seizure duration and titrated ST level in bifrontal (BF) ECT, which has not been previously studied, is examined here in addition to RUL ECT. We found an inverse relationship in RUL ECT but no relationship in BF ECT. Eighteen percent of RUL patients seized at the first stimulus level versus 40% of BF patients. Compared with previous studies, both our starting dose and the increments between stimuli were greater in BF ECT (50.4 mC) than in RUL ECT (25.2 mC). A relationship between stimulus dose and seizure length may have also been present in BF ECT had similar titration schedules been used for both electrode placements. Future studies using titration schedules with a lower initial dose and finer gradations between stimulus levels are needed to evaluate whether a relationship between stimulus dose and seizure duration exists in BF ECT.
机译：摘要：发现抑郁症患者的电抽搐治疗（ECT）发作的持续时间与滴定的右单侧（RUL）和双侧（BL）发作阈值（ST）水平成反比。人们认为这种反比关系反映了确定癫痫发作持续时间的神经过程。除RUL ECT外，本文还研究了癫痫发作持续时间与双额叶（BF）ECT中ST滴定水平之间的关系。我们在RUL ECT中发现相反的关系，但在BF ECT中发现没有关系。在第一次刺激时，有18％的RUL患者被抢救，而在BF患者中，这一比例为40％。与以前的研究相比，BF ECT（50.4 mC）的起始剂量和刺激之间的增量均大于RUL ECT（25.2 mC）。 BF ECT中也可能存在刺激剂量和癫痫发作长度之间的关系，如果在两个电极位置都使用了相似的滴定时间表。未来需要使用较低的初始剂量和更高的刺激水平梯度滴定方案进行研究，以评估BF ECT中是否存在刺激剂量和癫痫发作持续时间之间的关系。

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