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首页> 外文期刊>The Journal of hospital infection >A randomised controlled pilot study to compare filtration factor of a novel non-fit-tested high-efficiency particulate air (HEPA) filtering facemask with a fit-tested N95 mask.
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A randomised controlled pilot study to compare filtration factor of a novel non-fit-tested high-efficiency particulate air (HEPA) filtering facemask with a fit-tested N95 mask.

机译：一项随机对照的先导研究，用于比较新型非适合性测试的高效微粒空气（HEPA）过滤口罩和适合性测试的N95口罩的过滤因子。

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摘要

Use of a fit-tested N95 or FFP2 mask is recommended to protect against transmission of airborne pathogens. This poses considerable logistic problems when preparing for, or dealing with, an epidemic. Some of these problems might be overcome by use of a compact reusable high-efficiency particulate air filtering mask that can be cut to size. We carried out a randomised controlled cross-over study to compare the efficacy of such a mask (Totobobo, Dream Lab One Pte Ltd, Singapore) with fit-tested N95 masks (1860 or 1860s or 1862; 3M, St Paul, MN, USA) in 22 healthy volunteers. The median (interquartile range) reduction in airborne particle counts was significantly higher [193-fold (145-200)] for N95 masks than for Totobobo masks [135-fold (83-184)] (P<0.05). There was no statistically significant difference between the proportion of subjects achieving a reduction of > or =100-fold between N95 (19/22) and Totobobo (16/22) masks. We conclude that use of the Totobobo mask without fit testing cannot be recommended, but its performance is sufficiently promising to warrant further investigation.
机译：建议使用经过测试的N95或FFP2口罩，以防止空气传播的病原体传播。在准备或应对流行病时，这带来了相当大的后勤问题。这些问题中的某些问题可以通过使用紧凑的可重复使用的高效微粒空气过滤面罩来解决，该面罩可以缩小尺寸。我们进行了一项随机对照交叉研究，比较了这种口罩（Totobobo，Dream Lab One Pte Ltd，新加坡）与经过口试的N95口罩（1860或1860或1862; 3M，美国明尼苏达州圣保罗）的功效。 ）中的22名健康志愿者。 N95口罩的空气中颗粒计数的中位数（四分位数范围）减少明显高于Totobobo口罩的[193倍（145-200）] [135倍（83-184）]（P <0.05）。在N95（19/22）和Totobobo（16/22）口罩之间实现减少>或= 100倍的受试者比例之间没有统计学显着差异。我们得出的结论是，不建议使用未经托身测试的Totobobo面罩，但其性能足以保证进一步的研究。

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