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首页> 外文期刊>The Journal of Infectious Diseases >An Outbreak of Measles among Unvaccinated Young Adults and Measles Seroprevalence Study: Implications for Measles Outbreak Control in Adult Populations.
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An Outbreak of Measles among Unvaccinated Young Adults and Measles Seroprevalence Study: Implications for Measles Outbreak Control in Adult Populations.

机译：未接种疫苗的年轻人中的麻疹暴发和麻疹血清阳性率研究：对成年人口中麻疹暴发控制的意义。

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摘要

Measles incidence has declined significantly in the United States since the 1989-1991 resurgence. Several conditions, including pockets of underimmunization, international importation, and the inability to rapidly detect and contain cases, represent potential threats to this success. During the 1995-1996 winter holiday season, the Minnesota Department of Health investigated an outbreak of measles among unvaccinated young adults affiliated with a religious community. A total of 26 outbreak-associated cases of measles were identified; most case patients (65%) were 20-29 years of age (range, 18 months to 35 years). Although case patients had multiple opportunities to expose the general public, no subsequent transmission was identified despite extensive surveillance efforts. A measles seroprevalence survey of 508 Minnesota blood donors aged 20-39 years was conducted; 91% had serological evidence of immunity to measles. Our findings illustrate that high levels of population immunity can prevent transmissionof measles, despite multiple opportunities for exposure.
机译：自1989-1991年回潮以来，麻疹发病率在美国已大大下降。某些情况，包括免疫不足的地区，国际进口以及无法迅速发现和遏制病例，对成功的潜在威胁。在1995-1996年冬季假期期间，明尼苏达州卫生部调查了与宗教团体有联系的未接种疫苗的年轻人中的麻疹暴发。总共确定了26例与麻疹相关的暴发病例;大多数病例患者（65％）年龄在20-29岁之间（范围18个月至35岁）。尽管病例患者有多种机会向公众公开，但尽管进行了广泛的监测，仍未发现随后的传播途径。对508名明尼苏达州20至39岁的献血者进行了麻疹血清阳性率调查。 91％的人有血清免疫麻疹的证据。我们的研究结果表明，尽管有很多接触机会，但高水平的人群免疫仍可以预防麻疹的传播。

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