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首页> 外文期刊>The Journal of investigative dermatology. >Evaluation of skin viscoelasticity and anisotropy by measurement of speed of shear wave propagation with viscoelasticity skin analyzer.
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Evaluation of skin viscoelasticity and anisotropy by measurement of speed of shear wave propagation with viscoelasticity skin analyzer.

机译：通过使用粘弹性皮肤分析仪测量剪切波传播的速度来评估皮肤粘弹性和各向异性。

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Skin viscoelasticity was evaluated by a fast, noninvasive assay based on the measurement of the speed of elastic shear wave propagation in the skin by a new portable and user-friendly viscoelasticity skin analyzer. The range of speed of elastic shear wave propagation measured by viscoelasticity skin analyzer allows the evaluation of the stiffness of a wide spectrum of artificial materials as well as the viscoelasticity of skin of laboratory animals and human subjects. The directional nature of the measurement enables to monitor the anisotropy of the materials tested. The speed of elastic shear wave propagation was shown to have a positive correlation with the stiffness of the material tested. In symmetric contralateral areas of intact skin in rabbit ears, similar viscoelasticity and anisotropy were observed. Twenty-four hours after the induction of local edema by croton oil, skin stiffness and anisotropy were significantly increased. In healthy human subjects of both sexes significant variations in skin stiffness and anisotropy were observed in three different skin areas along the forearms, but the speed of elastic shear wave propagation was similar in the symmetric contralateral areas. Age (17-65 y) seemed to have a limited effect on the viscoelasticity of the forearm skin. Hydrating creams decreased the stiffness of the forearm skin for only approximately 3 h. The stiffness and anisotropy of the skin of the breasts in female volunteers (20-86 y) increased with age, but the speed of elastic shear wave propagation was similar in symmetric contralateral areas in the same individuals. Based on these results, we propose the application of the viscoelasticity skin analyzer in experimental and clinical practice for quantitative evaluation of skin condition.
机译：皮肤粘弹性是通过一种快速，无创的​​分析方法进行评估的，该方法基于使用新型便携式且用户友好的粘弹性皮肤分析仪对皮肤中弹性剪切波传播速度的测量。通过粘弹性皮肤分析仪测量的弹性剪切波传播的速度范围可以评估各种人工材料的刚度以及实验动物和人类受试者皮肤的粘弹性。测量的方向性使得能够监视被测材料的各向异性。弹性剪切波传播的速度与测试材料的刚度呈正相关。在兔耳完整皮肤的对称对侧区域中，观察到相似的粘弹性和各向异性。巴豆油诱发局部水肿后二十四小时，皮肤僵硬和各向异性明显增加。在两性健康的人类受试者中，沿着前臂在三个不同的皮肤区域观察到皮肤硬度和各向异性的显着变化，但是在对称对侧区域中，弹性剪切波的传播速度相似。年龄（17-65岁）似乎对前臂皮肤的粘弹性影响有限。保湿霜仅在大约3小时内降低了前臂皮肤的刚度。女性志愿者（20-86岁）的乳房皮肤刚度和各向异性随着年龄的增长而增加，但是在同一个人的对称对侧区域中，弹性剪切波的传播速度相似。基于这些结果，我们建议将粘弹性皮肤分析仪在实验和临床实践中用于定量评估皮肤状况。

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