...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of investigative dermatology. >Rapid and Continuous Increases in Incidence Rates of Basal Cell Carcinoma in the Southeast Netherlands Since 1973.
【24h】

Rapid and Continuous Increases in Incidence Rates of Basal Cell Carcinoma in the Southeast Netherlands Since 1973.

机译：自1973年以来，荷兰东南部基底细胞癌的发病率持续快速增加。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This study is aimed to determine the characteristics of the trends in incidence of basal cell carcinoma (BCC) in the Netherlands. We used incidence data of BCC from the Eindhoven Cancer Registry (Comprehensive Cancer Centre South) in the south of the Netherlands from 1973 to 2000. Data were age-adjusted and age-specific rates were calculated. Joinpoint and age-period-birth cohort modelling were applied. Between 1973 and 2000, age-adjusted incidence rates of BCC increased in both sexes, most markedly among (young) females. Recent increases were most marked on the trunk. The male data fitted age-drift models, suggesting a linear increase in rates over time, not attributable to either period- or cohort effects. In females, age-cohort-drift models described the data adequately, suggesting changes in intermittent UV exposures in subsequent cohorts. Incidence of BCC in the Netherlands is increasing rapidly, especially at body sites that are not chronically exposed to sunlight. The most likely explanation is an increased intermittent overexposure to UV radiation. This could have introduced an equal fractional increase in risk at all ages in all cohorts. There is no indication of an end to this trend in BCC.
机译：这项研究旨在确定荷兰基底细胞癌（BCC）发病率趋势的特征。我们使用了1973年至2000年荷兰南部埃因霍温癌症登记处（南方综合癌症中心）的BCC发病率数据。对数据进行了年龄调整并计算了特定年龄的比率。应用了联接点和年龄-出生队列模型。在1973年至2000年之间，按性别进行年龄调整的BCC发病率均有所上升，在（年轻）女性中最为明显。最近的涨幅最明显。男性数据拟合了年龄漂移模型，表明随着时间的流逝，比率呈线性增加，而不是归因于时期效应或队列效应。在女性中，年龄组漂移模型充分描述了数据，表明随后的队列中间歇性紫外线暴露发生了变化。荷兰的BCC发病率迅速增加，尤其是在没有长期暴露于阳光下的身体部位。最可能的解释是间歇性过度暴露于紫外线辐射。这可能在所有年龄段的所有年龄段的患儿中均引起了同等的风险增加。没有迹象表明BCC趋势已结束。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号