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首页> 外文期刊>The Journal of neuropsychiatry and clinical neurosciences >The role of self-awareness and cognitive dysfunction in Parkinson's disease with and without impulse-control disorder.
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The role of self-awareness and cognitive dysfunction in Parkinson's disease with and without impulse-control disorder.

机译：自我意识和认知功能障碍在有和没有冲动控制障碍的帕金森氏病中的作用。

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摘要

The aim of this study was to investigate the clinical, neuropsychological, and self-awareness correlates of impulse-control disorder (ICD) in a group of 17 Parkinson's disease (PD) subjects with an active ICD and a comparison group of 17 PD subjects without ICD. Self-awareness was assessed with the Beck Cognitive Insight Scale and patient-caregiver discrepancy scores from ratings on the Dysexecutive Questionnaire and the Everyday Memory Questionnaire-Revised. Self-awareness was comparable or increased in those with ICD, versus those without, and measures of neuropsychological functioning did not differ between the two groups. Those with ICD had more motor complications of PD therapy and were more likely to be on an antidepressant than those without ICD, whereas dopaminergic medication profiles were comparable between the two groups. In this group, PD patients with current ICDs were aware of their impulsivity. Although executive dysfunction may contribute to ICD behavior, it is not a necessary component. The awareness of the inability to resist these motivated behaviors may be a source of increased depression.
机译：这项研究的目的是调查17例帕金森氏病（PD）伴有活跃ICD的对照组和17例无PD的PD受试者的冲动控制障碍（ICD）的临床，神经心理学和自我意识相关性ICD。使用贝克认知洞察量表和患者照护者差异得分对自我意识进行评估，该得分来自执行障碍问卷和经修订的日常记忆问卷。与没有ICD的人相比，自我意识在有ICD的人中是相当的或有所增加，并且两组之间的神经心理学功能测量没有差异。与没有ICD的患者相比，具有ICD的患者具有PD治疗的更多的运动并发症，并且更有可能使用抗抑郁药，而两组的多巴胺能药物特征相当。在该组中，患有当前ICD的PD患者意识到其冲动性。尽管执行功能障碍可能会导致ICD行为，但这不是必需的组件。无法抵抗这些动机行为的意识可能是情绪低落的原因之一。

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