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首页> 外文期刊>The Journal of neuropsychiatry and clinical neurosciences >HIV-associated episodic memory impairment: evidence of a possible differential deficit in source memory for complex visual stimuli.
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HIV-associated episodic memory impairment: evidence of a possible differential deficit in source memory for complex visual stimuli.

机译：HIV相关的发作性记忆障碍：复杂视觉刺激的源记忆可能存在差异性不足的证据。

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摘要

HIV infection is often associated with frontal systems pathology and related deficits in the strategic encoding and retrieval aspects of episodic memory. However, no prior HIV studies have explicitly examined source memory, which refers to recall of information regarding the context in which a declarative memory was formed. Source memory is heavily reliant on frontal systems and strategic cognitive processes and is singly dissociable from the content of the memory (i.e., item memory), which is more dependent on medial temporal systems and automatic processes. The present study examined item and source memory in 60 individuals with HIV infection and 35 demographically similar seronegative participants. The primary finding of interest was a significant HIV effect on source (but not item) memory for complex visual stimuli. Follow-up correlational analyses showed a significant association between visual source memory errors and impairment on measures of executive functions, working memory, and higher-level list learning encoding strategies. These findings extend the hypothesized profile of strategic encoding and retrieval deficits in HIV to the construct of source memory, which may be differentially affected relative to item memory for complex visual stimuli.
机译：HIV感染通常与额叶系统病理以及情景记忆的策略性编码和检索方面的相关缺陷有关。但是，以前的HIV研究都没有明确检查源记忆，这是指回忆起形成声明式记忆的背景信息。源记忆严重依赖于额叶系统和策略性认知过程，并且与记忆的内容（即项目记忆）在某种程度上是分离的，后者更依赖于中间时态系统和自动过程。本研究检查了60名艾滋病毒感染者和35名人口统计学相似的血清阴性参与者的项目和来源记忆。感兴趣的主要发现是，HIV对复杂视觉刺激的来源（而非物品）记忆具有显着影响。后续的相关分析显示，视觉源记忆错误与执行功能，工作记忆和高级列表学习编码策略的度量值受损之间存在显着关联。这些发现将HIV的战略性编码和检索缺陷的假设特征扩展到了源记忆的构造，相对于复杂视觉刺激的项目记忆，其可能受到不同的影响。

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