Receptor-based screening assays: New perspectives in anti-doping control

Scippo ML; Willemsen P; Danyi S; Helbo V; Muller M; Martial J; Maghuin-Rogister G

首页> 外文期刊>Chromatographia >Receptor-based screening assays: New perspectives in anti-doping control

【24h】

Receptor-based screening assays: New perspectives in anti-doping control

机译：基于受体的筛选测定：反兴奋剂控制的新观点

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The so-called "growth promoters", steroid hormones and beta-agonists, are currently controlled by using hyphenated analytical methods (chromatography coupled to mass spectrometry) or, sometimes for screening purposes, on immunoassays. These methods are often too specific to allow an effective multianalyte control. To develop more efficient assays, the use of hormonal receptors as detection tools (receptor-based binding assays and cell-based assays) is proposed. Receptor-based assays represent useful tools in screening of hormonal residues in food, but they could also be applied in doping control (to detect "new" hormonal substances). Furthermore, these assays could be used to monitor the human exposure to endocrine disruptors.

机译：目前，所谓的“生长促进剂”，类固醇激素和β-激动剂是通过使用联用分析方法（色谱法与质谱联用）控制的，或者有时是出于筛选目的，通过免疫测定法来控制的。这些方法通常过于专一，无法进行有效的多分析物控制。为了开发更有效的测定，提出了使用激素受体作为检测工具（基于受体的结合测定和基于细胞的测定）。基于受体的测定法是筛选食品中荷尔蒙残留物的有用工具，但它们也可用于掺杂控制（以检测“新”荷尔蒙物质）。此外，这些测定法可用于监测人类对内分泌干扰物的暴露。

著录项

来源
《Chromatographia》 |2004年第1期|共5页
作者
Scippo ML; Willemsen P; Danyi S; Helbo V; Muller M; Martial J; Maghuin-Rogister G;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类分析化学;
关键词
receptor-based assays; multianalyte control; anti-doping control; hormonal residues in food; review; RADIORECEPTOR ASSAY; BIOASSAY;

机译：基于受体的检测;多分析物控制;反兴奋剂控制;食物中的激素残留;审查;放射性受体测定;生物测定;

相似文献

外文文献
中文文献
专利

1. Receptor-based screening assays: New perspectives in anti-doping control [J] . Scippo ML, Willemsen P, Danyi S, Chromatographia . 2004,第Suppla1期

机译：基于受体的筛选测定：反兴奋剂控制的新观点
2. Application of bar adsorptive microextraction (BAμE) for anti-doping control screening of anabolic steroids in urine matrices [J] . S.M. Ahmad, C. Almeida, N.R. Neng, Journal of chromatography, B. Analytical technologies in the biomedical and life sciences . 2014,第Null期

机译：棒吸附微萃取（BAμE）在尿基质中合成代谢类固醇的反兴奋剂对照筛选中的应用
3. New Perspectives from High-Content Screening Assays at No Extra Cost:Distinguishing Cell Types by Phenotypic Profiling of the Nucleus [J] . Alexander Schreiner Genetic Engineering & Biotechnology News: The Information Source of the Biotechnology Industry . 2018,第9期

机译：高含量筛选测定的新视角无额外成本：通过细胞核的表型分析来区分细胞类型
4. Evaluation of a novel metric for quality control in an RNA interference high throughput screening assay [C] . Xiaohua Douglas Zhang, Amy S. Espeseth, Namjin Chung, International Conference on Bioinformatics and Computational Biology . 2006

机译：评估RNA干扰高通量筛选测定中的质量控制的新型度量
5. Exploring the Factors That Affect World Anti-Doping Code Compliance: An Analysis of Peru’s and Bolivia’s National Anti-Doping Organizations [D] . Leon Cannock, Francisco. 2020

机译：探索影响世界反兴奋剂守则合规性的因素：秘鲁和玻利维亚国家反兴奋剂组织的分析
6. Original Fluorescent Ligand-Based Assays Open New Perspectives in G-Protein Coupled Receptor Drug Screening [O] . Martin Cottet, Orestis Faklaris, Jurriaan M. Zwier, 2011

机译：原始的基于荧光配体的检测方法在G-蛋白偶联受体药物筛选中开辟了新的前景
7. ASCLS Annual Meeting 2017: Official Abstracts of Submitted Papers, Case Studies and PostersEffective Incorporation of Performance Standards in Quality Control SystemsSubmandibular ZygomycosisRisk Management and Quality Control in Mass SpectrometryThe Significance of the Laboratory in the Work Up and Monitoring of Seemingly Independent Illnesses That In Fact Were InterrelatedThe Education Gap in Clinical MicrobiologyValidation of an Allelic Discrimination Assay for Drug MetabolismDevelopment of a High Resolution Melt Curve Assay to Detect Sickle Cell DiseasePhytochemical Effects on Bacterial BiofilmField Evaluation of Onsite Monitors for Surface Contamination by 5-fluorouracilComparison of Test Results for IHC, FISH and NGS when Screening for Molecular MarkersSevere Factor VII Deficiency in a NewbornValidation of Vysis LSI ALK and ROS1 Break Apart FISH ProbesA Prospective Study of Patients Diagnosed with Sarcoidosis: Nutrition, Health Assessment and Environmental ExposuresAssessment of Intake of Cinnamon Supplements on Hemoglobin A1c Levels in Pre-DiabeticsNGS Testing Helps to Identify New Treatment Opportunities for Advanced Solid Tumor Cancers Driven by Molecular AlterationsCause and Concern for Patients with B- cell Lymphoproliferative DisordersOral Presentation AbstractsInpatient Utilization of Point of Care Glucose Concomitant TestingWhat is That Bug in My Blood?Effects of Blood Banking Advanced Technology Practice Prior to Clinical Rotations on Clinical Laboratory Science Student OutcomesPlanting Your Lab Garden with Your OWN Seeds: A Novel Approach to the Laboratory Professional Shortage [O] . Selom Agboyi, Sean Ahrens, Zoe C. Brooks, 2017

机译：ASCLS年会2017年会议：提交文件的官方摘要，案例研究和女性效应融合在质量控制系统中的性能标准中的性能标准，质量光谱测定的质量控制在实际上的实验室中实验室的重要性，实际上是相互关联的疾病临床微生物术中的教育差距对高分辨率熔融曲线的药物代谢测定的等位基因辨别测定，以检测镰状细胞疾病对在IHC，鱼和NG的测试结果的表面污染的细菌生物膜对细菌污染物的评价。筛选分子标志物缺乏因子VII缺乏含量的流体LSI alk和ROS1分裂诊断患者的患者术语术后预期研究：营养，健康评估和环境曝光量表在糖尿病患者测试中的血红蛋白A1C水平的摄入量有助于确定通过分子改变驱动的先进实体肿瘤癌的新治疗机会，并且对B细胞淋巴抑制性疾病患者的患者的担忧伴随着护理点伴随的葡萄糖伴随测试的患者我的血液中的虫子？血库先进技术实践的影响在临床实验室科学学生临床旋转之前，用自己的种子将实验室花园脱颖而出：一种新的实验室专业短缺方法
8. Fiber Optic Microsensor for Receptor-Based Assays [R] . Block, M. J., Glass, T. R., Valdes, J. J. 1988

机译：用于基于受体的测定的光纤微传感器

Receptor-based screening assays: New perspectives in anti-doping control

摘要

著录项

相似文献

相关主题

期刊订阅