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首页> 外文期刊>The Journal of otolaryngology >Endoscopic treatment of cis-T2 glottic cancer with a CO(2) laser: preliminary results from a Canadian centre.
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Endoscopic treatment of cis-T2 glottic cancer with a CO(2) laser: preliminary results from a Canadian centre.

机译:内窥镜治疗顺式T2声门癌与CO(2)激光:来自加拿大中心的初步结果。

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In Canada, endoscopic resection using a CO(2) laser has been generally ignored as a treatment option. In this article, we present an introductory analysis of our clinical experience with the CO(2) laser at the QEII Health Sciences Centre in Halifax, Nova Scotia. Outcomes from a cohort of 36 patients with glottic cancer staged as Cis-T2 (7 Cis, 17 T1, 12 T2) who underwent endoscopic resection using a CO(2) laser between January 2002 and June 2005 were studied retrospectively. The mean follow-up was 16.2 months (range 0-41 months). At the time of the study, no patient had died of laryngeal disease, one patient had died of another disease, and one patient was lost to follow-up. There had been three recurrences in the cohort: two local recurrences and one recurrence in a regional lymph node. After salvage, all patients with recurrences were disease free at the time of the study. There were three postoperative complications in the cohort: one postoperative myocardial infarction, one case of respiratory distress postextubation, and one case of subcutaneous emphysema. The average time for the procedure was 0.97 hours (range 0.25-2.75 hours). The average postoperative length of stay was 1.2 days (range 0-12 days). Of 35 cases with follow-up, 60% had no reported problems with voice in their last visit and 11% reported consistent hoarseness or weakness. Although our oncologic results do require more follow-up, based on our positive experience thus far, we believe that endoscopic management of glottic cancer is a treatment option that may be underused in the Canadian health care system.
机译:在加拿大,使用CO(2)激光进行内窥镜切除术通常被视为一种治疗选择。在本文中,我们介绍了在新斯科舍省哈利法克斯的QEII健康科学中心使用CO(2)激光进行临床经验的介绍性分析。回顾性研究了2002年1月至2005年6月期间使用CO(2)激光进行内窥镜切除的36例声门癌患者的临床结果,分别为Cis-T2(7 Cis,17 T1,12 T2)。平均随访16.2个月(范围0-41个月)。在研究时,没有患者死于喉部疾病,一名患者死于另一种疾病,并且一名患者失去随访。该队列中有3例复发:2例局部复发和1例在局部淋巴结复发。抢救后,所有复发患者在研究时均无疾病。该队列有3例术后并发症:1例术后心肌梗死,1例拔管后呼吸窘迫和1例皮下气肿。该过程的平均时间为0.97小时(范围为0.25-2.75小时)。术后平均住院时间为1.2天(0-12天)。在35例接受随访的病例中,有60%的人在上次访视时未报告语音问题,而11%的人报告了持续的声音嘶哑或虚弱。尽管我们的肿瘤学结果确实需要更多的随访,但根据我们迄今为止的积极经验,我们相信声门癌的内镜治疗是加拿大医疗体系中可能未充分使用的一种治疗选择。

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