...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Journal of pediatrics >Gastric sensory and motor dysfunction in adolescents with functional dyspepsia.
【24h】

Gastric sensory and motor dysfunction in adolescents with functional dyspepsia.

机译：患有功能性消化不良的青少年的胃感觉和运动功能障碍。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVES: Validated, noninvasive studies were used to compare sensation and motor function of the upper gastrointestinal tract in adolescents with functional dyspepsia (FD) and in control subjects. STUDY DESIGN: Fifteen adolescents with FD and 15 healthy participants underwent standardized symptom assessment, a satiation nutrient drink test, and 13 C-Spirulina platensis breath test for gastric emptying of solids. Adolescents with FD also underwent measurements of fasting and postprandial gastric volume by means of single-photon emission computed tomography, and their results were compared with those from 15 healthy volunteers (age, 18 to 25 years). RESULTS: Compared with control subjects, adolescents with FD had significantly higher postprandial symptoms 30 minutes after reaching maximum satiation with the nutrient drink test and significant delay in the T 1/2 for gastric emptying of solids. Compared with healthy 18- to 25-year-old adults, adolescents had a diminished postprandial gastric volume response. By means of single-photon emission computed tomography, frequent baseline dyspeptic symptoms were associated with prolonged T 1/2 for gastric emptying and higher postprandial aggregate symptom score. A baseline increased severity of dyspepsia symptoms was associated with prolonged T 1/2 for gastric emptying. CONCLUSIONS: Adolescents with FD demonstrate increased postprandial symptoms after challenge, delayed gastric emptying, and a reduced gastric volume response to feeding.
机译：目的：经过验证的非侵入性研究用于比较患有功能性消化不良（FD）的青少年和对照组的上消化道的感觉和运动功能。研究设计：15名FD的青少年和15名健康的参与者进行了标准的症状评估，饱腹营养饮料测试和13 C-螺旋藻呼吸测试，以测定胃中的固体排空量。患有FD的青少年还通过单光子发射计算机断层摄影术对禁食和餐后胃容量进行了测量，并将其结果与15位健康志愿者（18至25岁）的结果进行了比较。结果：与对照组相比，FD的青少年在通过营养饮料测试达到最大饱腹感后30分钟出现明显更高的餐后症状，并且胃排空固体的T 1/2明显延迟。与健康的18至25岁的成年人相比，青少年的餐后胃容量反应减弱。通过单光子发射计算机断层扫描，频繁的基线消化不良症状与胃排空时间延长T 1/2和餐后聚集症状评分高有关。消化不良症状的基线严重程度增加与胃排空时间延长T 1/2有关。结论：FD青少年在激发后表现出餐后症状增加，胃排空延迟和对进食的胃容积反应降低。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号