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首页> 外文期刊>The Journal of pharmacy technology: jPT : official publication of the Association of Pharmacy Technicians >Erythropoietin forprevention and Treatment of Anemia in the Intensive Care Unit
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Erythropoietin forprevention and Treatment of Anemia in the Intensive Care Unit

机译：促红细胞生成素在重症监护病房预防和治疗贫血

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Objective: To evaluate and summarize the data on erythropoietin (EPO) use to prevent anemia in intensive care unit (ICU) patients.Data Sources: A literature search was performed using MEDLINE (1966-December 2003) using the key words erythropoietin, intensive care unit, anemia, and critically ill.Data Synthesis: Attempts to decrease the complications associated with anemia in ICU patients have recently focused on EPO use. Two comprehensive studies found that EPO significantly reduced the cumulative number of blood transfusions as compared to that of placebo. The assessing outcomes found no difference between the groups with respect to mortality rates, ventilation days, or length of stay.Conclusions: Available trials demonstrate reduced blood transfusions in ICU patients when EPO is administered. However, this result has not carried over as a defined clinical benefit. EPO use should be reserved for patients with longer hospital stays who are at risk for frequent blood transfusions as a comprehensive blood conservation strategy in the ICU.
机译：目的：评估和总结有关使用促红细胞生成素（EPO）预防重症监护病房（ICU）患者贫血的数据。数据来源：文献检索使用MEDLINE（1966年12月至2003年12月），关键词为促红细胞生成素，重症监护数据综合：尝试减少ICU患者贫血相关并发症的方法最近集中在EPO的使用上。两项综合研究发现，与安慰剂相比，EPO显着减少了累计输血次数。评估结果发现两组之间在死亡率，通气天数或住院时间方面无差异。结论：现有试验表明，在使用EPO时ICU患者的输血减少。但是，该结果尚未延续为明确的临床益处。应将EPO用于住院时间较长且有频繁输血风险的患者，作为ICU中的综合血液保存策略。

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