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首页> 外文期刊>The Journal of Nutritional Biochemistry >Chromium picolinate and conjugated linoleic acid do not synergistically influence diet- and exercise-induced changes in body composition and health indexes in overweight women
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Chromium picolinate and conjugated linoleic acid do not synergistically influence diet- and exercise-induced changes in body composition and health indexes in overweight women

机译：吡啶甲酸铬和共轭亚油酸不会协同影响超重女性饮食和运动引起的身体成分和健康指数变化

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This study assessed the effects of combined chromium picolinate (CP) and conjugated linoleic acid (CLA) supplementation on energy restriction and exercise-induced changes in body composition, glucose metabolism, lipid lipoprotein profile and blood pressure in overweight, premenopausal women. For 12 weeks, 35 women [age 36pl1 years (meanplS.E.M.); BMI 28.0pl0.5 kg/m2] were counseled to consume a 2092 kJ/day (500 kcal/day) energy deficit diet and performed 30 min of moderate-intensity walking or jogging 5 days/week. The women were randomly assigned to ingest either CP-CLA [400 og chromium (Cr), 1.8 g CLA in 2.4 g tonalin oil, n=19] or placebo (<0.1 og Cr, 2.4 g canola oil, n=16). Compared to baseline, urinary Cr excretion increased 22-fold, plasma CLA isomer 18:2 (c9,t11) content increased 79% and plasma CLA isomer 18:2 (t10,c12) became detectable in CP-CLA and were unchanged in Placebo. Over time, body weight decreased 3.5pl0.5% (CP-CLA -2.6pl0.5; placebo -2.5pl0.5 kg) and fat mass decreased 8.9pl1.3% (CP-CLA -2.7pl0.5, placebo -2.4pl0.5 kg), with no differences in responses between groups. Fasting blood hemoglobin A1c, plasma glucose and insulin, a homeostatic assessment of insulin resistance, serum total cholesterol (CHOL), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol, triacylglycerol (TG), CHOL/HDL ratio, TG/HDL ratio and sitting systolic and diastolic blood pressures were not changed over time or influenced by CP-CLA. The use of a combined CP and CLA supplement for 3 months does not affect diet- and exercise-induced changes in weight and body composition or improve indexes of metabolic and cardiovascular health in young overweight women.
机译：这项研究评估了补充吡啶甲酸铬（CP）和共轭亚油酸（CLA）对能量限制和运动引起的超重，绝经前妇女身体成分，葡萄糖代谢，脂质脂蛋白谱和血压变化的影响。为期12周，共有35名妇女[年龄36pl1岁（平均年龄：E.M。）;建议BMI 28.0pl0.5 kg / m2消耗2092 kJ /天（500 kcal /天）的能量缺乏饮食，并进行30分钟的中等强度步行或慢跑，每周5天。这些妇女被随机分批摄入CP-CLA [400克铬（Cr），2.4克Tonalin油中的1.8克CLA，n = 19]或安慰剂（<0.1克铬，2.4克菜籽油，n = 16）。与基线相比，尿Cr排泄增加了22倍，血浆CLA异构体18：2（c9，t11）含量增加了79％，血浆CLA异构体18：2（t10，c12）在CP-CLA中变得可检测到，而在安慰剂中没有变化。随着时间的推移，体重下降3.5pl0.5％（CP-CLA -2.6pl0.5;安慰剂-2.5pl0.5 kg），脂肪量下降8.9pl1.3％（CP-CLA -2.7pl0.5，安慰剂- 2.4pl0.5公斤），两组之间的反应无差异。空腹血红蛋白A1c，血糖和胰岛素，胰岛素抵抗的稳态评估，血清总胆固醇（CHOL），高密度脂蛋白胆固醇（HDL），低密度脂蛋白胆固醇，三酰甘油（TG），CHOL / HDL比值，TG / HDL比值和坐姿收缩压和舒张压均不会随时间变化或受CP-CLA影响。连续三个月使用CP和CLA组合补充剂不会影响饮食和运动引起的体重和身体组成的变化，也不会改善年轻超重女性的代谢和心血管健康指标。

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