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首页> 外文期刊>The journal of obstetrics and gynaecology research >Mandatory single embryo transfer policy dramatically decreases multiple pregnancy rates
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Mandatory single embryo transfer policy dramatically decreases multiple pregnancy rates

机译：强制性单胎移植政策显着降低了多胎妊娠率

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Aim: The aim of this study is to determine the effect of a mandatory single embryo transfer (SET) policy on pregnancy rates and multiple pregnancy rates in intracytoplasmic sperm injection (ICSI) cycles. Methods: One hundred and twenty-eight patients (154 cycles) underwent ICSI before the Turkish Ministry of Health's legislation, 55 patients (69 cycles) underwent ICSI after the legislation (day-3 embryo transfers only) and 35 patients (39 cycles) who underwent ICSI after the legislation (day-5 embryo transfers only). Results: Groups were comparable regarding the women's mean age and body mass index. The number of embryos transferred (2.7 ± 0.5 vs 1.0 ± 0.0 vs 1.0 ± 0.0) was significantly higher in group I, compared to group II and group III. Clinical pregnancy per embryo transfer (40.8% vs 15.1% vs 36.1%) and live birth rate (37.7% vs 13.2% vs 30.6%) were significantly lower in group II when compared to group I and group III. Multiple pregnancy rates (39.6% vs 0.0%, vs 0.0%) were significantly higher in group I when compared to group II and III. Implantation rates were significantly higher in group III when compared to group I and group II. Miscarriage rates were comparable among the groups. Conclusion: The mandatory SET policy caused a dramatic decrease of multiple pregnancy rates. Mandatory SET with only day-3 embryo transfers decreased the pregnancy rates but this detrimental effect was not seen in cycles with day-5 embryo transfers.
机译：目的：本研究的目的是确定强制性单胚移植（SET）策略对胞浆内精子注射（ICSI）周期中的妊娠率和多重妊娠率的影响。方法：在土耳其卫生部立法之前，有128例患者（154个周期）接受了ICSI;立法之后（仅第3天的胚胎移植），有55例患者（69个周期）进行了ICSI，而在土耳其立法通过后仅进行了3天的胚胎移植（35个周期）立法后接受了ICSI（仅第5天胚胎移植）。结果：各组在女性平均年龄和体重指数方面具有可比性。与第二组和第三组相比，第一组移植的胚胎数量（2.7±0.5 vs 1.0±0.0 vs 1.0±0.0）明显更高。与I组和III组相比，II组的每次胚胎移植临床妊娠率（40.8％vs 15.1％vs 36.1％）和活产率（37.7％vs 13.2％vs 30.6％）显着降低。与第二和第三组相比，第一组的多胎妊娠率（39.6％vs 0.0％，vs 0.0％）显着更高。与第一组和第二组相比，第三组的植入率明显更高。各组的流产率相当。结论：强制性SET策略导致多次妊娠率急剧下降。仅进行第3天胚胎移植的强制性SET降低了妊娠率，但在进行第5天胚胎移植的周期中未观察到这种有害作用。

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