首页> 外文期刊>The Journal of Prosthetic Dentistry >Effect of toothbrushing on the toxicity of casting alloys.
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Effect of toothbrushing on the toxicity of casting alloys.

机译:牙刷对铸造合金毒性的影响。

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STATEMENT OF PROBLEM: The biological properties of casting alloys have been assessed largely under passive conditions. The effect of common intraoral stresses such as brushing, toothpastes, and low pH on alloy toxicity are not known. PURPOSE: This study assessed the toxicity of 5 types of casting alloys commonly used in prosthodontics after toothbrushing, brushing in an acidic environment, or brushing with toothpaste. These toxicities were compared with those observed without any brushing. MATERIAL AND METHODS: Au-Pt, Au-Pd, Pd-Cu-Ga, Ni-Cr-Be, and Ni-Cr (no Be) alloys were brushed for 48 hours in a toothbrushing machine at 90 strokes/minute and 200g force. Alloys were brushed with either saline at pH 7, saline at pH 4 (acidified with sodium lactate), or saline with 1:7 (wt/wt) toothpaste. After the brushing regimen, the cytotoxicity of the alloys was assessed in a standard in vitro test. Cytotoxicities of the alloys after different brushing treatments were compared with unbrushed (control) specimens. Analysis of variance (ANOVA) and Tukey multiple comparison intervals (alpha=.05) were used to identify significant differences among brushing conditions. RESULTS: Brushing at pH 7 significantly increased the toxicity of the Pd-Cu-Ga alloy (15% to 20% over unbrushed specimens). Brushing at pH 4 increased the toxicity of the Au-Pt and Au-Pd alloys by 30% and the Pd-Cu-Ga alloy by >40%. The Ni-based alloys were not affected by acid. After being brushed with toothpaste, both Ni-based alloys were significantly more toxic, but Ni-Cr-Be was the worst, increasing more than 60% in toxicity over the controls. The toxicity of the Au-Pd alloy also increased significantly (15%). CONCLUSION: Brushing dental casting alloys may increase their cytotoxicity in vitro, but the increase depends heavily on the alloy type and brushing condition.
机译:问题陈述:铸造合金的生物学性能已在被动条件下进行了评估。常见的口腔内应力(如刷牙,牙膏和低pH)对合金毒性的影响尚不清楚。目的:本研究评估了牙刷,在酸性环境中刷牙或用牙膏刷牙后,修复修复中常用的5种铸造合金的毒性。将这些毒性与未刷牙时观察到的毒性进行了比较。材料和方法:在牙刷机中以90冲程/分钟和200g的力将Au-Pt,Au-Pd,Pd-Cu-Ga,Ni-Cr-Be和Ni-Cr(无Be)合金刷毛48小时。 。用pH 7的盐水,pH 4的盐水(用乳酸钠酸化)或含1:7(wt / wt)牙膏的盐水刷洗合金。刷牙后,在标准的体外试验中评估合金的细胞毒性。将不同刷牙处理后的合金的细胞毒性与未刷牙(对照)样品进行了比较。方差分析(ANOVA)和Tukey多个比较间隔(alpha = .05)用于确定刷牙条件之间的显着差异。结果:在pH 7时刷涂可显着提高Pd-Cu-Ga合金的毒性(相对于未刷涂的样品,其毒性为15%至20%)。在pH 4时刷涂可将Au-Pt和Au-Pd合金的毒性提高30%,将Pd-Cu-Ga合金的毒性提高> 40%。 Ni基合金不受酸影响。在用牙膏刷牙后,两种镍基合金的毒性都明显更高,但镍铬铍合金的毒性最差,毒性比对照组高60%以上。 Au-Pd合金的毒性也显着增加(15%)。结论:刷牙铸造合金可能会增加其体外细胞毒性,但这种增加在很大程度上取决于合金类型和刷牙条件。

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