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首页> 外文期刊>The Journal of Prosthetic Dentistry >Survival analysis and clinical evaluation of implant-retained prostheses in oral cancer resection patients over a mean follow-up period of 10 years.
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Survival analysis and clinical evaluation of implant-retained prostheses in oral cancer resection patients over a mean follow-up period of 10 years.

机译：平均随访期为10年的口腔癌切除患者中植入物固定假体的生存分析和临床评估。

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STATEMENT OF PROBLEM: Dental implants have been increasingly used for prosthodontic rehabilitation of patients following oral tumor resection and postsurgical radiotherapy. However, only a few long-term studies have examined the implant survival rate and other factors related to prosthodontic treatment in oral tumor resection patients. PURPOSE: The purpose of this study was to evaluate the long-term survival of dental implants and implant-retained prostheses in oral cancer resection patients. MATERIAL AND METHODS: Ninety-three patients (63 men, 30 women) with a mean age of 59 years (range of 26-89 years) received 435 implants after the resection of a head and neck tumor. Twenty-nine patients received postsurgical radiotherapy prior to implant placement. The factors related to implant survival or failure were monitored over a mean observation period of 10.3 years (range of 5 to 161 months). Prosthodontic rehabilitation was evaluated with respect to the rates of technical failures and complications. Datawere analyzed using a Kaplan-Meier curve and comparisons were made with the log-rank test or the Wilcoxon test (a=.05). RESULTS: Of the 435 implants, 43 implants were lost; the cumulative survival rate was 92%, 84%, and 69% after 3.5, 8.5, and 13 years, respectively. Twenty-eight implants in 6 patients were counted as lost since the patients had died. Twenty-nine irradiated patients received 124 implants, of which 6 implants were lost prior to prosthodontic rehabilitation. In 68 patients with 78 rigid bar-retained dentures, only minor technical complications were identified. However, all 25 fixed implant-supported restorations had no technical component failures and did not require technical maintenance. CONCLUSIONS: This study demonstrates that implant-retained and -supported prostheses in oral cancer resection patients, irrespective of the cancer treatment procedure, show lower long-term survival rates than those in patients without prior cancer surgery. Rigid fixation of the implant-supported prosthesis appears to minimize the complication rates. The poor implant survival rate was due to the higher mortality rate among these patients, and not to a lack of osseointegration.
机译：问题陈述：牙科植入物已被越来越多地用于口腔肿瘤切除和术后放射治疗后的牙齿修复。但是，只有少数长期研究检查了口腔肿瘤切除患者的种植体存活率和与修复治疗相关的其他因素。目的：本研究的目的是评估口腔癌切除患者中牙种植体和种植体固位假体的长期存活率。材料与方法：93例平均年龄为59岁（26-89岁）的患者（63例男性，30例女性）在切除头颈部肿瘤后接受了435枚植入物。 29名患者在植入植入物之前接受了术后放射治疗。在平均10.3年（5到161个月）的平均观察期内监测与植入物存活或失败相关的因素。评估了修复修复的技术失败率和并发症发生率。使用Kaplan-Meier曲线分析数据，并通过对数秩检验或Wilcoxon检验（a = .05）进行比较。结果：435颗植入物中，有43颗丢失。在3.5、8.5和13年后，累积生存率分别为92％，84％和69％。自患者死亡以来，有6例患者中的28枚植入物被计为丢失。 29名接受辐照的患者接受了124枚植入物，其中6枚植入物在修复修复之前丢失。在68例具有78个刚性棒状固位假牙的患者中，仅发现了较小的技术并发症。但是，所有25个由植入物支持的固定修复物均没有技术组件故障，并且不需要技术维护。结论：这项研究表明，无论采用何种癌症治疗方法，口腔癌切除患者中植入物固定和支撑的假体的长期生存率均低于未进行过癌症手术的患者。植入物支撑假体的刚性固定似乎可以最大程度地降低并发症发生率。植入物存活率差的原因是这些患者的死亡率较高，而不是缺乏骨整合。

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